The clinical specialty of adult nephrology has enjoyed spectacular growth during the past three decades. Such a statement is no less true for pediatric nephrology. This book stands in quiet testimony to that fact. Practitioners of pediatric nephrology are now concerned with the diagnosis and treat ment of young patients with a widened spectrum of primary and sec ondary diseases of the kidneys and urinary tract, hypertension and disorders of water, electrolyte and acid-base metabolism. Their science, deriving from an exciting blend of physiology, morphology, pathology, immunology, biochemistry, microbiology, genetics and pharmacology, must also include an understanding of human developmental biology an insight that colleagues who practice adult nephrology require to a somewhat lesser extent. Dramatic, continuing advances in our understanding of the pathogen esis, pathophysiology, diagnosis and treatment of kidney diseases has led to a cascade of books and monographs on various aspects of the subject. Nevertheless, in view of the clear emergence of pediatric nephrology as a distinct medical specialty, it is most appropriate that a practical book, which focuses almost exclusively on approaches to the evaluation and diagnosis of young patients with kidney disease and related disorders, should appear. In that sense this book is unique. It provides an easily accessible, practical compendium or guide to the clinical investigation of all facets of kidney disease in children. Its special and unique emphasis is directed toward various approaches to the evaluation of such patients and the interpretation of associated laboratory or radiographical data.

This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time to address all the topics in the field of critical care nephrology in children in a unique book which is the first of its kind. This book covers the basics as well as advances in the field of Critical Care Nephrology. Each chapter is dedicated to practical aspects of a particular topic elucidating various management decision points. Each chapter is also accompanied with algorithms, figures and protocols in tabulated format. Information on how to manage specific conditions are contextualized with relevant background anatomy, physiology and biochemistry and practical examples. At the end of the chapter, there are key learning points. Paediatricians, nephrologists and paediatric intensivists, as well as paediatric critical care and nephrology nurses in all countries will find this book an invaluable reference text.

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

The provision of optimal dialysis therapy to children requires a thorough understanding of the multi-disciplinary manner in which the pediatric patient is affected by renal insufficiency. Knowledge of the technical aspects of peritoneal dialysis, hemodialysis and continuous renal replacement therapy must be complemented by attention to issues such as anemia, renal osteodystrophy, hypertension, growth, cognitive development, nutrition, nursing care and the psychosocial adaptation of the child and family to chronic disease. The inaugural edition of Pediatric Dialysis provides a comprehensive review of these and other related topics with a singular emphasis on the unique aspects of their application to children. With authoritative, clinically relevant, well-referenced chapters written by a host of recognized international experts who emphasize key aspects of contemporary management, Pediatric Dialysis has been designed to serve as a primary resource to all clinicians involved in the care of the pediatric dialysis patient.

End-stage renal disease is a devastating diagnosis to the patient, family and their care provider. This book covers all aspects of chronic kidney disease from a general description to its psychological impact on the adolescent and lastly its progression to end-stage and dialysis. It details the important aspects of the patient’s journey from diagnosis to their final destination including transplant and discussion of the medications used. It includes chapters on important etiologies of chronic kidney disease in adolescence, addressing the particular challenges a provider may be faced with in caring for this age group, and finally transition of their care to adult care providers. Written by experts in the field of pediatrics and nephrology Adolescents with Chronic Kidney Disease is the definitive resource in diagnosing and transitioning patients with chronic kidney disease.

The provision of optimal dialysis therapy to children requires a thorough understanding of the multi-disciplinary manner in which the pediatric patient is affected by renal insufficiency. Knowledge of the technical aspects of peritoneal dialysis, hemodialysis and continuous renal replacement therapy must be complemented by attention to issues such as anemia, renal osteodystrophy, hypertension, growth, cognitive development, nutrition, nursing care and the psychosocial adaptation of the child and family to chronic disease. The inaugural edition of Pediatric Dialysis provides a comprehensive review of these and other related topics with a singular emphasis on the unique aspects of their application to children. With authoritative, clinically relevant, well-referenced chapters written by a host of recognized international experts who emphasize key aspects of contemporary management, Pediatric Dialysis has been designed to serve as a primary resource to all clinicians involved in the care of the pediatric dialysis patient.