This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.

This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIST, melanoma, colorectal cancer, breast cancer, and endocrine cancer.

A resource that combines oncologic principles with treatment plans for the surgical management of neoplasms Textbook of General Surgical Oncology is a practical and comprehensive reference that offers authoritative coverage of a wide variety of oncologic concepts and disorders. The book opens with detailed discussion of the general principles of molecular biology, cancer epidemiology, surgical oncology, radiation oncology, medical oncology, immunotherapy, nuclear imaging, and molecular diagnostics. The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, bone, head/neck, brain, lung, mediastinum, breast, pleura, peritoneum, as well as tumors that affect various systems, including the endocrine, gastrointestinal, hepatobiliary, genitourinary, gynecologic, and hematopoietic. · Each chapters is written by an internationally recognized expert on the topic · Learning aids include chapter-ending Q&A and Practical Pearls · Outstanding review for the new General Surgical Oncology certification examination

In this issue of Surgical Oncology Clinics of North America, Guest Editor Clifford Ko, MD has assembled the top experts concerning Outcomes Research in Oncology. Topics in this issue will include: Currently Available Quality Initiatives in Surgical Oncology; Variation in Mortality After High Risk Cancer Surgery: Failure to Rescue; Readmission as a Quality Measure Following High Risk Cancer Surgery; Randomized Controlled Trials in Surgical Oncology: Where Do We Stand?; Lymph Node Staging in GI Malignancies; Racial and Socioeconomic Disparities in Cancer Care; Patient Safety in Surgical Oncology: Perspective from the Operating Room; Value Based Health Care: A Surgical Oncologist Perspective; Monitoring the Delivery of Cancer Care: Commission on Cancer and National Cancer Data Base; Prediction Tools in Surgical Oncology; Collaboration With the Community Cancer Center: Benefit for All; and Evaluating the Appropriateness of Cancer Care in the United States.

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

In this issue of Surgical Oncology Clinics, guest editor Dr. Natalie Lui brings her considerable expertise to the topic of Oncology Imaging: Updates and Advancements. Treatment planning and implementation in oncology relies heavily on cancer imaging modalities. In this issue, top experts in the field of oncology imaging discuss the latest imaging techniques and modalities for the most common malignancies, such as lung, breast, and liver cancer, as well as a timely article on 3D CT reconstruction and printing to aid surgical planning. - Contains 10 practice-oriented topics including fluoroestradiol imaging of ER+ breast cancer; advances in imaging to aid segmentectomy for lung cancer; 3D computed tomography reconstruction and printing to aid surgical planning; molecular imaging of head and neck cancer; contrast-enhanced intraoperative ultrasound of the liver; and more. - Provides in-depth clinical reviews on oncology imaging, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.