Characterizes the toxicologic and adverse health effects (AHE) info. for chlorine dioxide (CD), a hazardous gas that is used as a bleach at paper pulp mills, and in public water-treatment facilities. This profile includes: (A) exam¿n. and interpretation of available toxicologic info. and epidemiologic evaluations on CD to ascertain the levels of significant human exposure and the assoc. chronic health effects; (B) A determination of whether adequate info. on the health effects of CD is avail. to determine levels of exposure that present a significant risk to human health of acute, subacute, and chronic health effects; and (C) Identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of AHE in humans. Charts and tables.