This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

A reproduction of the original book Tobacco: Growing, Curing, & Manufacturing published in 1886. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.

Whereas most crops drive farmers apart as they compete for the best prices, the price controls on tobacco bring growers together. The result is a culture unlike any other in America, one often forgotten or overlooked as federal and state governments fight over the spoils of the tobacco settlement. Tobacco Culture describes the process of raising a crop of burley from the perspective and experience of the farmers themselves. In the process of gathering information for the book, the authors performed most steps in the tobacco production process, from dropping plants, burning seedbeds, topping, and cutting to stripping and baling the finished product. Van Willigen and Eastwood document both present practices and historical developments in tobacco farming at the very moment a way of life stands poised for dramatic change. In addition to growing practices, the authors found other common threads linking growers and tobacco producing regions. Where tobacco is grown, it often becomes the major cash crop and carries the health of the economy. Farmer Oscar Richardson states, "It's bread and butter. It's the industry of the community, the state as a whole.... You take tobacco out of Kentucky and this farmland wouldn't be worth a nickel." Combining cultural anthropology and oral history, John van Willigen and Susan Eastwood have created a remarkable portrait of the heart of the burley belt in Central Kentucky.

The bulk of the world’s tobacco is produced in low- and middle-income countries. In order to dissuade these countries from implementing policies aimed at curbing tobacco consumption (such as increased taxes, health warnings, advertising bans and smoke-free environments), the tobacco industry claims that tobacco farmers will be negatively affected and that no viable, sustainable alternatives exist. This book, based on original research from three continents, exposes the myths behind these claims.

Tobacco use kills more people than any other addiction and we know that addiction starts in childhood and youth. We all agree that youths should not smoke, but how can this be accomplished? What prevention messages will they find compelling? What effect does tobacco advertisingâ€"more than $10 million worth every dayâ€"have on youths? Can we responsibly and effectively restrict their access to tobacco products? These questions and more are addressed in Growing Up Tobacco Free, prepared by the Institute of Medicine to help everyone understand the troubling issues surrounding youths and tobacco use. Growing Up Tobacco Free provides a readable explanation of nicotine's effects and the process of addiction, and documents the search for an effective approach to preventing the use of cigarettes, chewing and spitting tobacco, and snuff by children and youths. It covers the results of recent initiatives to limit young people's access to tobacco and discusses approaches to controls or bans on tobacco sales, price sensitivity among adolescents, and arguments for and against taxation as a prevention strategy for tobacco use. The controversial area of tobacco advertising is thoroughly examined. With clear guidelines for public action, everyone can benefit by reading and acting on the messages in this comprehensive and compelling book.

How did Bright Flue-Cured Tobacco come to dominate the industry? In her sweeping history of the American tobacco industry, Barbara Hahn traces the emergence of the tobacco plant’s many varietal types, arguing that they are products not of nature but of economic relations and continued and intense market regulation. Hahn focuses her study on the most popular of these varieties, Bright Flue-Cured Tobacco. First grown in the inland Piedmont along the Virginia–North Carolina border, Bright Tobacco now grows all over the world, primarily because of its unique—and easily replicated—cultivation and curing methods. Hahn traces the evolution of technologies in a variety of regulatory and cultural environments to reconstruct how Bright Tobacco became, and remains to this day, a leading commodity in the global tobacco industry. This study asks not what effect tobacco had on the world market, but how that market shaped tobacco into types that served specific purposes and became distinguishable from one another more by technologies of production than genetics. In so doing, it explores the intersection of crossbreeding, tobacco-raising technology, changing popular demand, attempts at regulation, and sheer marketing ingenuity during the heyday of the American tobacco industry. Combining economic theory with the history of technology, Making Tobacco Bright revises several narratives in American history, from colonial staple-crop agriculture to the origins of the tobacco industry to the rise of identity politics in the twentieth century.