The Physics of Three Dimensional Radiation Therapy presents a broad study of the use of three-dimensional techniques in radiation therapy. These techniques are used to specify the target volume precisely and deliver radiation with precision to minimize damage to surrounding healthy tissue. The book discusses multimodality computed tomography, complex treatment planning software, advanced collimation techniques, proton radiotherapy, megavoltage imaging, and stereotactic radiosurgery. A review of the literature, numerous questions, and many illustrations make this book suitable for teaching a course. The themes covered in this book are developed and expanded in Webb's The Physics of Conformal Radiotherapy and the two may be used together or in successive semesters for teaching purposes.

Radiation therapy is in the process of continual change, fueled by advances in computer technology, but also aided by the contributions of several disciplines such as physics, mathematics, radiological diagnostics, neurosurgery, and mechanical and electrical engineering. Based on the 3D imaging techniques CT and MRI, a complete change from the 2D consideration of the radiotherapy problem has taken place, leading to 3D treatment planning and to completely new treatment delivery systems. A 3D approach allows for a dramatic rethinking of the following central therapy issues: positioning, targeting, and dose and risk calculation. Major advances have been made in recent years in conformal or stereotactic techniques, in dosimetry, the target volume concept as well as clinical studies. The advances are reflected in the papers collected here from the international symposium '3D Radiation Treatment: Technological Innovations and Clinical Results' held in Munich in March 1999. The reports present the newest technical developments and clinical applications. New conformal and stereotactic technologies are discussed. Clinical results are presented in the treatment of lung cancer, prostate cancer, and brain tumors. The role of growth factors and cytokines in the pathogenesis of radiation injury is examined as are mechanisms in the development of normal tissue damage and their significance for understanding tolerated radiation dose. Included are reports on endovascular brachytherapy and new tools of 3D brachytherapy. This timely book will be of particular interest to radiation oncologists and related clinical practitioners, biologists and physicists.

Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

With contributions by numerous experts

This book provides a first comprehensive summary of the basic principles, instrumentation, methods, and clinical applications of three-dimensional dosimetry in modern radiation therapy treatment. The presentation reflects the major growth in the field as a result of the widespread use of more sophisticated radiotherapy approaches such as intensity-modulated radiation therapy and proton therapy, which require new 3D dosimetric techniques to determine very accurately the dose distribution. It is intended as an essential guide for those involved in the design and implementation of new treatment technology and its application in advanced radiation therapy, and will enable these readers to select the most suitable equipment and methods for their application. Chapters include numerical data, examples, and case studies.

Radiation therapy is in the process of continual change, fueled by advances in computer technology, but also aided by the contributions of several disciplines such as physics, mathematics, radiological diagnostics, neurosurgery, and mechanical and electrical engineering. Based on the 3D imaging techniques CT and MRI, a complete change from the 2D consideration of the radiotherapy problem has taken place, leading to 3D treatment planning and to completely new treatment delivery systems. A 3D approach allows for a dramatic rethinking of the following central therapy issues: positioning, targeting, and dose and risk calculation. Major advances have been made in recent years in conformal or stereotactic techniques, in dosimetry, the target volume concept as well as clinical studies. The advances are reflected in the papers collected here from the international symposium '3D Radiation Treatment: Technological Innovations and Clinical Results' held in Munich in March 1999. The reports present the newest technical developments and clinical applications. New conformal and stereotactic technologies are discussed. Clinical results are presented in the treatment of lung cancer, prostate cancer, and brain tumors. The role of growth factors and cytokines in the pathogenesis of radiation injury is examined as are mechanisms in the development of normal tissue damage and their significance for understanding tolerated radiation dose. Included are reports on endovascular brachytherapy and new tools of 3D brachytherapy. This timely book will be of particular interest to radiation oncologists and related clinical practitioners, biologists and physicists. ℗℗