Cancer threatens the lives of people around the world. Women, in particular, are at risk of certain cancers with a genetic cause. Certain mutations in the BRCA1 and BRCA2 genes put mothers and daughters at risk of breast and ovarian cancers. Unlike many cancers that most commonly occur after age 60, these inheritable cancers threaten women’s lives, health and fertility even when they are young, before most would even begin to go for annual mammogram screenings to check for breast cancer. Three Daughters, Three Journeys takes on the biggest health issue of our time from a global perspective with three heroines fighting for their lives against cancer. Marzena, a Polish oncology nurse, has spent her life treating child patients with cancer. Then, she confronts it in her own family and her own body. Kamola, a rural Indian girl, knows she has symptoms of the same disease that took her mother, but feels afraid to discuss it with her father and brothers, knowing her family cannot afford medical treatment. Kamola confides in Dr Rini Mishra, a doctor testing a new treatment called Neelazin, using a bacterial anticancer protein in food, to destroy cancer cells. Selena, a wealthy woman of color in Chicago, finds out about her genetic risks of breast and ovarian cancer. She has a choice of preventative surgery that will save her life but remove any chance of having children. As she meets women who struggle to afford cancer treatment, Selena dedicates her life to providing affordable homes and counseling to families affected by the disease. Although the drug Neelazin is fictional, the possibility of new cancer treatments using bacterial anticancer proteins is being researched now. A problem with the current chemotherapy for cancer treatment is the high toxicity of most of these drugs, as these drugs can enter both normal and cancer cells, though preferably cancer cells, causing the death of normal cells as well that are important in maintaining health. Another problem is that current chemotherapeutic drugs mostly target a single or few key steps that are important for cancer growth and proliferation and inhibit the growth of cancer cells. The cancer cells respond by quickly changing these single targets, thereby becoming resistant to the drugs, as is reflected in stage IV cancer patients. An alternative to chemotherapy would be to exploit the bacterial evolutionary wisdom and use certain proteins that can have preferential entry to cancer cells in order to minimize normal cell toxicity and multiple targets in cancer cells through protein–protein complex formation, thus reducing resistance development in cancer cells. An interesting advantage of protein drugs is to express them as part of food, and some recent research seems to suggest that oral consumption of such foods may allow the therapeutic protein to reach the blood stream to target the cancer. Women with the genetic risk factors could soon have the choice of taking a pill or such anticancer protein-expressing food to treat or prevent cancer, rather than removing the healthy tissue of the breasts and ovaries. Hopefully, they would not have to choose between fertility and survival, as is the implied message in this book, fictional as it is at this time.

From the fertile hills of a tiny village near Jerusalem to the elegant townhouses of Georgetown, Three Daughters is a historical saga that chronicles the lives, loves, and secrets of three generations of Palestinian Christian women. Born in rural Palestine, just before the dawn of the twentieth century, Miriam adores her father and is certain his love will protect her, but she soon finds that tradition overrides love. Uprooted by war, Miriam enters a world where the old constraints slip away with thrilling and disastrous results. Miriam's rebellious daughter, Nadia, is thrilled with the opportunity for a modern life that her elite education provides. But when she falls in love with an outsider, the clan reins her back with a shocking finality. Nijmeh, Nadia's daughter, is an only child and the path her father, the sheik, sets for her is fraught with difficulties, yet it prepares her for her ultimate journey to America, where she finds her future. Each woman, in her own time and in her own way, experiences a world in transition through war and social change...and each must stretch the bounds of her loyalty, her courage, and her heart.

A secret adoption, a quest for identity, and a love that could change her life forever. Margaret Lenora Caine has never fit the mold her mother set for her. When Maggie discovers proof she was adopted, the rift between them only tears deeper. Feeling the sting of betrayal, Maggie requests permission to visit her grandmother in Little Rock, Arkansas. There she'll set her sights on her dream of becoming a successful dress designer and maybe find her true identity in the process. Her father's one condition is that she must be travel with her young aunt and her father's handsome business partner, Charles Stanton-the man who once held her affections. Charles Stanton, a thriving businessman, has taken a calculated risk by joining forces with Maggie's father in a joint venture. When asked to chaperone his new partner's sister-in-law and daughter on a cross-country trip, Charles sees it as an opportunity to strengthen their business ties. Though he initially sets his sights on Maggie's charming and composed aunt as a potential wife, Charles soon finds himself increasingly captivated by Maggie's resilience and charm. With each passing mile, the bond between Maggie and Charles deepens, challenging both Maggie's plans and her heart. Will the love growing between them help her embrace her identity-or complicate her search for what truly matters in life?

Includes a partial Heming's family tree.

An Indie Next Pick The stunning, timely new novel from the acclaimed, internationally bestselling author of The Architect's Apprentice and The Bastard of Istanbul. Peri, a married, wealthy, beautiful Turkish woman, is on her way to a dinner party at a seaside mansion in Istanbul when a beggar snatches her handbag. As she wrestles to get it back, a photograph falls to the ground--an old polaroid of three young women and their university professor. A relic from a past--and a love--Peri had tried desperately to forget. Three Daughters of Eve is set over an evening in contemporary Istanbul, as Peri arrives at the party and navigates the tensions that simmer in this crossroads country between East and West, religious and secular, rich and poor. Over the course of the dinner, and amidst an opulence that is surely ill-begotten, terrorist attacks occur across the city. Competing in Peri's mind however are the memories invoked by her almost-lost polaroid, of the time years earlier when she was sent abroad for the first time, to attend Oxford University. As a young woman there, she had become friends with the charming, adventurous Shirin, a fully assimilated Iranian girl, and Mona, a devout Egyptian-American. Their arguments about Islam and feminism find focus in the charismatic but controversial Professor Azur, who teaches divinity, but in unorthodox ways. As the terrorist attacks come ever closer, Peri is moved to recall the scandal that tore them all apart. Elif Shafak is the number one bestselling novelist in her native Turkey, and her work is translated and celebrated around the world. In Three Daughters of Eve, she has given us a rich and moving story that humanizes and personalizes one of the most profound sea changes of the modern world.

An astonishing story that puts a human face on the ongoing debate about immigration reform in the United States, now updated with a new Epilogue and Afterword, photos of Enrique and his family, an author interview, and more—the definitive edition of a classic of contemporary America Based on the Los Angeles Times newspaper series that won two Pulitzer Prizes, one for feature writing and another for feature photography, this page-turner about the power of family is a popular text in classrooms and a touchstone for communities across the country to engage in meaningful discussions about this essential American subject. Enrique’s Journey recounts the unforgettable quest of a Honduran boy looking for his mother, eleven years after she is forced to leave her starving family to find work in the United States. Braving unimaginable peril, often clinging to the sides and tops of freight trains, Enrique travels through hostile worlds full of thugs, bandits, and corrupt cops. But he pushes forward, relying on his wit, courage, hope, and the kindness of strangers. As Isabel Allende writes: “This is a twenty-first-century Odyssey. If you are going to read only one nonfiction book this year, it has to be this one.” Praise for Enrique’s Journey “Magnificent . . . Enrique’s Journey is about love. It’s about family. It’s about home.”—The Washington Post Book World “[A] searing report from the immigration frontlines . . . as harrowing as it is heartbreaking.”—People (four stars) “Stunning . . . As an adventure narrative alone, Enrique’s Journey is a worthy read. . . . Nazario’s impressive piece of reporting [turns] the current immigration controversy from a political story into a personal one.”—Entertainment Weekly “Gripping and harrowing . . . a story begging to be told.”—The Christian Science Monitor “[A] prodigious feat of reporting . . . [Sonia Nazario is] amazingly thorough and intrepid.”—Newsday

A Seattle Times Best Book of the Year A Buzzfeed Best Nonfiction Book of the Year "Nimura paints history in cinematic strokes and brings a forgotten story to vivid, unforgettable life." —Arthur Golden, author of Memoirs of a Geisha In 1871, five young girls were sent by the Japanese government to the United States. Their mission: learn Western ways and return to help nurture a new generation of enlightened men to lead Japan. Raised in traditional samurai households during the turmoil of civil war, three of these unusual ambassadors—Sutematsu Yamakawa, Shige Nagai, and Ume Tsuda—grew up as typical American schoolgirls. Upon their arrival in San Francisco they became celebrities, their travels and traditional clothing exclaimed over by newspapers across the nation. As they learned English and Western customs, their American friends grew to love them for their high spirits and intellectual brilliance. The passionate relationships they formed reveal an intimate world of cross-cultural fascination and connection. Ten years later, they returned to Japan—a land grown foreign to them—determined to revolutionize women’s education. Based on in-depth archival research in Japan and in the United States, including decades of letters from between the three women and their American host families, Daughters of the Samurai is beautifully, cinematically written, a fascinating lens through which to view an extraordinary historical moment.