This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the field of transplantation, have written the foreword for the book. The volume spans such topics as skin rejection, immune monitoring, stem cell-based immunomodulatory strategies, costimulatory blockade, tolerance induction, chronic rejection, ischemia reperfusion injury, nerve regeneration, cortical reintegration, and small and large animal models for reconstructive transplantation. The book is intended for biomedical researchers and basic scientists in the field of reconstructive transplantation, transplant immunology and regenerative medicine, as well as clinicians, surgeons and multidisciplinary specialists, who are practicing or interested in this novel and exciting field. Postgraduate fellows and students will also find it a valuable reference.

There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. - Provides detailed description of clinical trials in cell transplantation - Review of current therapeutic approaches - Coverage of the broad range of diseases addressed by cell therapeutics - Discussion of stem cell biology and its role in transplantation

Written by experts from London’s renowned Royal Free Hospital, Textbook of Plastic and Reconstructive Surgery offers a comprehensive overview of the vast topic of reconstructive plastic surgery and its various subspecialties for introductory plastic surgery and surgical science courses. The book comprises five sections covering the fundamental principles of plastic surgery, cancer, burns and trauma, paediatric plastic surgery and aesthetic surgery, and covers the breadth of knowledge that students need to further their career in this exciting field. Additional coverage of areas in which reconstructive surgery techniques are called upon includes abdominal wall reconstruction, ear reconstruction and genital reconstruction. A chapter on aesthetic surgery includes facial aesthetic surgery and blepharoplasty, aesthetic breast surgery, body contouring and the evolution of hair transplantation.The broad scope of this volume and attention to often neglected specialisms such as military plastic surgery make this a unique contribution to the field. Heavily illustrated throughout, Textbook of Plastic and Reconstructive Surgery is essential reading for anyone interested in furthering their knowledge of this exciting field. This book was produced as part of JISC's Institution as e-Textbook Publisher project. Find out more at https://www.jisc.ac.uk/rd/projects/institution-as-e-textbook-publisher

3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. - Discusses new possibilities in tissue engineering with 3D printing - Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues - Reviews emerging technologies in addition to commercial techniques

With coverage of nearly twice the number of flaps as the previous edition, Flaps and Reconstructive Surgery, 2nd Edition provides trainees and practicing surgeons alike with the detailed, expert knowledge required to ensure optimal outcomes. It includes chapters and expert commentaries from more than 100 authors and world-renowned leaders in the field, while brand-new cases and high-quality illustrations focused on flap harvest, markings, and reconstruction keep you abreast of today's latest developments. - Includes high-quality illustrations of regional anatomy, flap anatomy, and step-by-step flap dissections, as well as clear photographs demonstrating successful reconstructions. - Detailed case studies illustrate how to optimize every aspect of care for the reconstructive surgery patient, including the postoperative period and long-term follow-up. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices. - Expanded video library of narrated surgical procedures covers most of the flaps used in reconstructive surgery. - Brand-new section on reconstruction takes an algorithmic approach to the reconstruction of defects around the body. - Features chapters covering the entire spectrum of reconstructive surgery, including head and neck reconstruction, chest wall reconstruction, abdominal wall, upper and lower extremity, and facial reanimation. - Content focuses on both local and free flaps. - New section on reconstructive transplant surgery highlights major topics such as face and hand transplantations, abdominal wall transplantation, uterus transplantation, and nerve allotransplantation.

The first textbook of its kind dealing with composite tissue allograft and allograft transplantation, provides an excellent overview on the subject. It provides a clear description of the current status of the transplant of every composite tissue allograft already performed and others which are still at the basic experimental level.The editors of the book, who also contribute chapters in their expertise, are world renowned surgeons. This book opens with an introductory chapter on the history of this type of transplantation and then details the clinical experience in each graft such as hand, larynx, face, uterus and the related histopathology, immunosuppression and immunomodulation.A multidisciplinary and comprehensive presentation of the various aspects of this new area of transplantation will allow the reader to understand the complexity and the challenges of composite tissue transplantation. A number of important topics are analyzed and discussed in detail, such as the ethical, medicolegal, psychological and immunological implications. New rehabilitation techniques and strategies, together with innovative tools for the functional evaluation of the transplanted parts, are highlighted. A section on the experimental work underlines what lies ahead of us./a

This book offers comprehensive coverage of reconstructive transplantation surgery. It represents the culmination of decades of practice and research surrounding reconstructive transplantation, including transplantation of upper and lower extremities, face, abdominal wall etc. from donor to recipient. Chapters are organized from in a formulaic manner covering anatomy, approach, considerations and preparations, case studies, and outcomes. Extensive details on the most challenging parts of transplantation including donor selection, vascular considerations, and the latest research on immunosuppressant drugs, makes this book a triumph of experience from the experts of the world renowned Cleveland Clinic. This book, as is the case with the clinic itself, brings together experts from teams across disciplines in a collaborative effort to illustrate decision-making for various large tissue transplants. Diverse perspectives from head and neck surgery, plastic surgery, craniofacial surgery, microvascular surgery, transplant surgery and even psychology contribute to the wealth of knowledge collected in this volume and broaden the readership. Reconstructive Transplantation is a must-have resource for surgeons, physicians, and residents in the fields of head and neck surgery, plastic surgery, craniofacial surgery, and trauma surgery.