This novel, part romance, part science fiction, part thriller, is the story of a famous child prodigy in mathematics and music, Dianna Utterson, who, later as a PHD student in biophysics, develops a fool-proof, anti-mutagenic vaccine against AIDS. It's also a story of a jealous medical student's obsession to steal the genetic code and Fourier analysis developed by his lover, Dianna, needed by his future pharmaceutical corporation to manufacture her wonder AIDS drug. The book's most interesting sub-plot is the Jesuit-controlled, Pythagorean secrecy surrounding her cure and its conflict with traditional Vatican theology. With clear allusions to quantum physics, and molecular biology as developed by the American James Watson, and the British Scientists Francis Crick and Rosalind Franklin, this novel is ideal for high school and college-age students, and those readers interested in the magic of bio-medical research in its quest to find cures for mankind's most elusive diseases. It's a lasting work that inspires readers to appreciate science through the uplifting experience of a disarming, beatific heroine, Dianna Utterson. --- Wayne Kappel, Ph.D, recipient of the Distinguished Teacher White House Commission on Presidential Scholars award, 1997

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.

This is the first full-length biography of British historian Frances Yates, author of such acclaimed works as Giordano Bruno and The Hermetic Tradition and The Art of Memory, one of the most influential non-fiction books of the twentieth century. Jones’s book explores Yates’ remarkable life and career and her interest in the mysterious figure of Giordano Bruno and the influence of the Hermetic tradition on the culture of the Renaissance. Her revolutionary way of viewing history, literature, art, and the theater as integral parts of the cultural picture of the time period did much to shape modern interdisciplinary approaches to history and literary criticism. Jones focuses not only on the particulars of Yates’ life, but also sheds light on the tradition of female historians of her time and their contributions to Renaissance scholarship. In addition to her insightful commentary on Yates’ academic work, Jones quotes from Frances’ diaries and the writings of those who were close to her, to shed light on Yates’ private life. This biography is significant for those with an interest in literary criticism, women’s history, scientific history, or the intellectual atmosphere of post-war Britain, as well as those interested in the Hermetic tradition.

This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.