To scientists engaged in research on the cellular mechanisms in the mammalian brain, concepts of "motivation" seem to be a logical neces sity, even if they are not fashionable. Immersed in the detailed, time consuming research required to deal with mammalian nerve cells, we usually pay scant attention to the more global brain -behavior questions that have arisen from decades of biological and psychological studies. We felt it was time to confront these issues-namely, how far has neuro biological investigation come in uncovering mechanisms by which moti vational signals influence behavior? At Rockefeller University, we have recently held a course on this subject. We restricted our treatment to those motivational systems most tractable to physiological approaches, and invited scientists skilled in both behavioral issues and physiological techniques to participate. This volume results from that course. The deans and administration at Rockefeller University provided much help in planning the course, and the staff of Springer-Verlag assisted in planning the book. Gabriele Zummer helped organize both the course and the processing of book chapters. They all deserve our thanks. December 1981 Donald W. Pfaff Professor of Neurobiology and Behavior Rockefeller University Contents Part One: Concepts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Chapter 1 Donald W. Pfaff Motivational Concepts: Definitions and Distinctions . . . . . . . . . . 3 Motivation: A Brief Review of Concepts. . . . . . . . . . . . . . . . . . . . . . . . . . 5 Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Reinforcement, Reward . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Incentive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Arousal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Emotion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Motivation Is a Unitary Behavioral Concept with Multiple Neurophysiological Mechanisms. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Chapter 2 Alan N.

This volume covers the current status of research in the neurobiology of motivated behaviors in humans and other animals in healthy condition. This includes consideration of the psychological processes that drive motivated behavior and the anatomical, electrophysiological and neurochemical mechanisms which drive these processes and regulate behavioural output. The volume also includes chapters on pathological disturbances in motivation including apathy, or motivational deficit as well as addictions, the pathological misdirection of motivated behavior. As with the chapters on healthy motivational processes, the chapters on disease provide a comprehensive up to date review of the neurobiological abnormalities that underlie motivation, as determined by studies of patient populations as well as animal models of disease. The book closes with a section on recent developments in treatments for motivational disorders.

Neal E. Miller's pioneering work in experimental psychology has earned him worldwide respect. This second in a two-volume collection of his work brings together forty-three of Miller's most important and representative essays on learning, motivation, and their physiological mechanisms. They were selected on the basis of their current relevance and their historical significance at the time they were published. In order to emphasize the main themes, essays on a given topic have been grouped together.Learning, Motivation, and Their Physiological Mechanisms begins when the author first discovered the thrill of designing and executing experiments to get clear-cut answers concerning the behavior of children and of rats. The first study was one of the earliest ones on the behavioral effects of the recently synthesized male hormone, testosterone. The second was one of the earliest studies demonstrating the value of using a variety of behavioral techniques to investigate the motivational effects of a physiological intervention. The next studies investigated the satisfying and rewarding effects of food or water in the stomach versus in the mouth and the thirst-inducing and reducing effects of hyper- and hypotonic solutions, respectively, injected into the brain. The last study describes a technique devised for extending the analysis of the mechanism of hunger to the effects of humoral factors in the blood.The study is completed with an examination of trial-and-error learning that was motivated by direct electrical stimulation of the brain and rewarded by the termination of such stimulation. Other studies show that the stimulation via such electrodes not only elicits eating, but also has the principal motivational characteristics of normal hunger. The conclusion deals with a series of experiments that overthrows strong traditional beliefs by proving that glandular and visceral responses mediated by the autonomic nervous system are subject to instrumental learning, which can be

The Wiley Handbook on the Cognitive Neuroscience of Learning charts the evolution of associative analysis and the neuroscientific study of behavior as parallel approaches to understanding how the brain learns that both challenge and inform each other. Covers a broad range of topics while maintaining an overarching integrative approach Includes contributions from leading authorities in the fields of cognitive neuroscience, associative learning, and behavioral psychology Extends beyond the psychological study of learning to incorporate coverage of the latest developments in neuroscientific research

Explores the relationship between the brain and our motivation to do things, analysing psychological, physiological and combined approaches.

This comprehensive overview of research, issues, and theories relating to sexual orientation, behavior, and identity by experts in various disciplines is unique in providing both historical perspectives and a synthesis of the recent advances in understanding homosexuality and heterosexuality. Drawing from biological and psychological research, this handbook critically reviews the major theories about sexual orientation and examines each theory on the basis of empirical support. One section summarizes recent developments in genetic and neuroanatomic research. Another section discusses problems with sexual performance among heterosexual, homosexual, and bisexual persons. A third section provides overviews of clinical disorders or sexual deviations. Various chapters clarify the distinction between sexual disorders, such as pedophilia, and sexual variations, such as homosexuality. Chapters also examine important social issues relevant to sexual orientation, such as disability, prejudice, aging, and gender roles. Experts address the continuing controversy over the feasibility of altering sexual orientation; new developments in treating different types of problems; and changing perspectives today. This handbook is designed for the use of educators, students, and researchers in the social and behavioral sciences.