Chronic pain is not a life sentence If you are one of the 100 million people who suffer from chronic pain, you may be feeling hopeless and helpless, relying on endless medications that don't work, feeling worse and worse. But there is hope -- and help. The innovative program at the acclaimed Las Vegas Recovery Center, at which Dr. Mel Pohl is Medical Director, has helped thousands of sufferers to reduce chronic pain without the use of painkillers. The Pain Antidote shares this program's concrete tools and strategies, offering: Cutting-edge research on how pain affects your brain How your emotions affect your experience of pain A comprehensive program, including a four-week Jump Start plan Pain-reducing gentle exercises and health-supporting foods And much more.

Written by a distinguished team of authors experienced in various areas of chronic pain management and addiction treatment, this comprehensive workbook was developed for anyone struggling with chronic pain and dependence on opioids or other painkillers. Based on a program that has proven highly successful in a treatment setting.

A holistic approach to confronting chronic pain Pain is one of the most important and urgent issues facing the world today. Millions are afflicted with pain, and it is the most frequent reason Americans seek medical attention annually. More than 50 million people in the United States suffer from chronic pain. In fact, pain is a worldwide pandemic with no end in sight. In a conversational and easy-to-read format, A Day Without Pain reviews the physical and psychological problems associated with pain, as well as ways to assess it. It also examines methods to treat pain in a comprehensive holistic manner so that health and function can be restored without the use of prescription painkillers.

Self-help books don't seem to work. Few of the many advantages of modern life seem capable of lifting our collective mood. Wealth—even if you can get it—doesn't necessarily lead to happiness. Romance, family life, and work often bring as much stress as joy. We can't even agree on what "happiness" means. So are we engaged in a futile pursuit? Or are we just going about it the wrong way? Looking both east and west, in bulletins from the past and from far afield, Oliver Burkeman introduces us to an unusual group of people who share a single, surprising way of thinking about life. Whether experimental psychologists, terrorism experts, Buddhists, hardheaded business consultants, Greek philosophers, or modern-day gurus, they argue that in our personal lives, and in society at large, it's our constant effort to be happy that is making us miserable. And that there is an alternative path to happiness and success that involves embracing failure, pessimism, insecurity, and uncertainty—the very things we spend our lives trying to avoid. Thought-provoking, counterintuitive, and ultimately uplifting, The Antidote is the intelligent person's guide to understanding the much-misunderstood idea of happiness.

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.