M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

"The purpose of the National Statement is to promote ethically good human research. Fulfilment of this purpose requires that participants be accorded the respect and protection that is due to them. It also involves the fostering of research that is of benefit to the community. The National Statement is therefore designed to clarify the responsibilities of: institutions and researchers for the ethical design, conduct and dissemination of results of human research ; and review bodies in the ethics review of research. The National Statement will help them to meet their responsibilities: to identify issues of ethics that arise in the design, review and conduct of human research, to deliberate about those ethical issues, and to justify decisions about them"--Page 6.

This title provides a comprehensive look at the factors threatening health globally and the measures that can be taken to promote health in communities. The book argues that social, economic and environmental factors are as vital to health as biological and genetic factors.

In Medicine of Australian Mammals, more than 30 experts present the most current information available on the medical management of all taxa of Australian native mammals. This comprehensive text is divided into two parts. The first includes chapters on general topics relevant to the medical management of captive and free-ranging Australian native mammals such as: veterinary considerations for the rescue, treatment, rehabilitation and release of wildlife; veterinary aspects of hand-rearing orphaned marsupials; marine mammal strandings and the role of the veterinarian; and wildlife health investigation and necropsy of Australian mammals. The second part covers the medicine of specific taxa of Australian native mammals. Detailed information on taxonomy, distribution, biology, anatomy, physiology, reproduction, husbandry, nutrition, physical and chemical restraint, clinical pathology, hand-rearing, diseases, zoonoses, therapeutics, reproductive management and surgery is included. This practical, one-source reference is complemented by detailed photographs and illustrations, as well as tables listing reproductive and physiological data, diets, haematology and biochemistry values, and drug formularies. Appendices include a checklist of the mammals of Australia and its territories and a guide to the identification of common parasites of Australian mammals. Medicine of Australian Mammals is clinically oriented and is a must-have for veterinary clinicians, no matter how experienced. The book will also be of use to veterinary students, researchers, biologists, zoologists, wildlife carers and other wildlife professionals.