Winner of the Elizabeth Longford Prize for Historical Biography 2016 Frederick Hamiton-Temple-Blackwood, 1st Marquess of Dufferin and Ava, enjoyed a glittering career which few could equal. As Viceroy of India and Governor-General of Canada, he held the two most exalted positions available under the Crown, but prior to this his achievements as a British ambassador included restoring order to sectarian conflict in Syria, helping to keep Canada British, paving the way for the annexation of Egypt and preventing war from breaking out on India's North-West Frontier. Dufferin was much more than a diplomat and politician, however: he was a leading Irish landlord, an adventurer and a travel writer whose Letters from High Latitudes proved a publishing sensation. He also became a celebrity of the time, and in his attempts to sustain his reputation he became trapped by his own inventions, thereafter living his public life in fear of exposure. Ingenuity, ability and charm usually saved the day, yet in the end catastrophe struck in the form of the greatest City scandal for forty years and the death of his heir in the Boer War. With unique access to the family archive at Clandeboye, Andrew Gailey presents a full biography of the figure once referred to as the 'most popular man in Europe'.

Congenital malformations are worldwide occurrences striking in every condition of society. These severe physical abnormalities which are present at birth and affecting every part of the body happen more often than usually realized, once in every 33 births. The most common, after heart defects, are those of the neural tube (the brain and spinal cord) which happen in as many as one in every 350 births. They have been noted as curiousities in man and beast throughout recorded history and received great attention in our time by various fields of study, for example, their faulty prenatal development by embryologists, familial patterns by geneticists, causation by environmentalists and variability by population scientists. Attention turned much in recent years to the relation of these malformations to deficiency of a particular dietary ingredient, folic acid, a subject this book analyzes in depth. The greatest conundrum of all, which this latest matter like so much else hinges on, is the amazing fact of the tremendous, almost universal decrease in the frequency of these anomalies since early in the 20th century. The puzzle is What can this downward trend possibly mean? and at bottom Whether it is part of a long-term cyclical pattern . This fascinating biological phenomenon is explored in the book together with various other topics.