Social isolation has serious repercussions for people and communities across the globe, yet knowledge about this phenomenon has remained rather limited – until now. The first multidisciplinary study to explore this issue, Social Isolation in Modern Society integrates relevant research traditions in the social sciences and brings together sociological theories of social networks and psychological theories of feelings of loneliness. Both traditions are embedded in research, with the results of a large-scale international study being used to describe the extent, nature and divergent manifestations of social isolation. With a new approach to social inequality, this empirically based study includes concrete policy recommendations, and presents a clear insight into personal, social and socio-economic causes and the consequences of social isolation.

Soybean protei ns are wi de 1 y used inhuman foods ina vari ety of forms, including baby formulas, flour, soy protein concentrates, soy protein isolates, soy sauces, textured soy fibers, and tofu. The presence of inhibitors of digestive enzymes in soy proteins impairs nutritional quality and possible safety of this impportant legume. Normal processing conditions based on the use of heat do not completely inactivate these inhibitors, so that residual amounts of plant protease inhibitors are consumed by animals and man. Inhibitors of digestive enzymes are present not only in legumes, such as soybeans, lima beans, and kidney beans, but also in nearly all plant foods, including cereals and potatoes, albeit in much smaller amounts. The antinutritional effects of inhibitors of proteolytic enzymes have been widely studied and can be ameliorated by processing and/or sulfur amino acid fortification. A more urgent concern is reports that rats fed diets containing even low levels of soybean-derived inhibitors, which are found in foods such as soy-based baby formulas, may develop over their lifespan pancreatic lesions leading eventually to neoplasia or tumor formation. On the other hand, recent stUdies suggest that certain enzyme inhibitors from plant foods may prevent cancer formation in other tissues. A key question, therefore, is whether inhibitors from plant foods constitute a human health hazard.

This book constitutes the proceedings of the 10th International Symposium on NASA Formal Methods, NFM 2018, held in Newport News, VA, USA, in April 2018. The 24 full and 7 short papers presented in this volume were carefully reviewed and selected from 92 submissions. The papers focus on formal techniques and other approaches for software assurance, their theory, current capabilities and limitations, as well as their potential application to aerospace, robotics, and other NASA-relevant safety-critical systems during all stages of the software life-cycle.