This volume contains some research papers from the International Conference on Information Technology and Management organized by the Hong Kong Polytechnic University, in conjunction with the Institute of Systems Management (ISM). It comprises 30 selected and refereed papers in the development of enabling technologies, electronic commerce and knowledge management, and IT systems and applications. These papers feature the results of the latest research in the areas of information systems, enabling technologies, and business management, as well as potential applications in industries including education, finance, logistics, medical tourism, and IT services.