We live in a world that's constantly redesigned. Today's redesign is tomorrow's vintage look. But times of crisis rapidly change the picture. Suddenly, the whole world is in dire need of a proper redesign. From capitalism to communication, from work to supply chains, from cities to office space - it's hard to find an area of our lives that's not due for an overhaul. This is a challenge, but also a huge opportunity: to design a better world. Edited by Matthias Schrader and Volker Martens. With contributions by Payal Arora, Axel Averdung, Kristina Bonitz, Azeem Azhar, Genevieve Bell, Amy McLennan, Benedict Evans, Daisy Ginsberg, Rafael Kaufmann, Sohail Inayatullah, David Mattin, Miriam Meckel, Léa Steinacker, Thomas Müller, Ramez Naam, Tijen Onaran, Pamela Pavliscak, Ben Sauer, Laëtitia Vitaud, Albert Wenger.

Never before have Australians worked so hard yet felt so unhappy. With anxiety rising at unprecedented levels, now is the time to stop and consider whether there could be another way to live. We renovate our houses, but what about our lives? The Great Life Redesign is an inspirational yet practical guidebook to help you reshape the life you have to create one you'll love. The Great Life Redesign is an inspiring guidebook to help you reshape the life you have to create one you'll love. The practical, simple to apply techniques and inspiring personal stories included in this book will show you how. Learn the secrets of one-on-one coaching with Caroline Cameron, an executive, career and lifestyle coach. Based on her experiences working with hundreds of professionals across Australia and beyond, she steps you through the process of designing a blue print for the life you really want. Key features: Helps the reader to create a blue print for making real and actionable change, including career, relationships, wealth and finances, health, home, personal growth, environment, leisure and spirituality. Use to instantly repair parts of your life that could be better or as a step-by-step plan for a major life renovation. Includes practical, simple to apply techniques and inspiring personal stories Written for professionals, middle income, burnt-out city slickers, corporate refugees, disillusioned 30-somethings, mid life crisis sufferers, baby boomers whose super and retirement dreams evaporated in the GFC, dedicated parents who want the best for their kids, and anyone who suspects that there's more to life but don't know what it is or how to get it.

Explains the concepts of particles, fields, relativity, and quantum mechanics, describes how recent discoveries have changed our view of the universe, and discusses the search for an ultimate, unified theory

Recent scientific and technological advances have accelerated our understanding of the causes of disease development and progression, and resulted in innovative treatments and therapies. Ongoing work to elucidate the effects of individual genetic variation on patient outcomes suggests the rapid pace of discovery in the biomedical sciences will only accelerate. However, these advances belie an important and increasing shortfall between the expansion in therapy and treatment options and knowledge about how these interventions might be applied appropriately to individual patients. The impressive gains made in Americans' health over the past decades provide only a preview of what might be possible when data on treatment effects and patient outcomes are systematically captured and used to evaluate their effectiveness. Needed for progress are advances as dramatic as those experienced in biomedicine in our approach to assessing clinical effectiveness. In the emerging era of tailored treatments and rapidly evolving practice, ensuring the translation of scientific discovery into improved health outcomes requires a new approach to clinical evaluation. A paradigm that supports a continual learning process about what works best for individual patients will not only take advantage of the rigor of trials, but also incorporate other methods that might bring insights relevant to clinical care and endeavor to match the right method to the question at hand. The Institute of Medicine Roundtable on Value & Science-Driven Health Care's vision for a learning healthcare system, in which evidence is applied and generated as a natural course of care, is premised on the development of a research capacity that is structured to provide timely and accurate evidence relevant to the clinical decisions faced by patients and providers. As part of the Roundtable's Learning Healthcare System series of workshops, clinical researchers, academics, and policy makers gathered for the workshop Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches. Participants explored cutting-edge research designs and methods and discussed strategies for development of a research paradigm to better accommodate the diverse array of emerging data resources, study designs, tools, and techniques. Presentations and discussions are summarized in this volume.