Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

The World Health Organization's Global Technical Strategy for Malaria 2016- 2030 has been developed with the aim to help countries to reduce the human suffering caused by the world's deadliest mosquito-borne disease. Adopted by the World Health Assembly in May 2015 it provides comprehensive technical guidance to countries and development partners for the next 15 years emphasizing the importance of scaling up malaria responses and moving towards elimination. It also highlights the urgent need to increase investments across all interventions - including preventive measures diagnostic testing treatment and disease surveillance- as well as in harnessing innovation and expanding research. By adopting this strategy WHO Member States have endorsed the bold vision of a world free of malaria and set the ambitious new target of reducing the global malaria burden by 90% by 2030. They also agreed to strengthen health systems address emerging multi-drug and insecticide resistance and intensify national cross-border and regional efforts to scale up malaria responses to protect everyone at risk.

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Towards Malaria Elimination - A Leap Forward was started to mark the occasion for renewed commitment to end malaria transmission for good (the WHO's call for "Malaria Free World" by 2030). This book is dedicated for the benefit of researchers, scientists, program and policy managers, students and anyone interested in malaria and other mosquito-borne diseases with the goal of sharing recent information on success stories, innovative control approaches and challenges in different regions of the world. Some main issues that emerged included multidrug-resistant malaria and pandemic risk, vaccines, cross-border malaria, asymptomatic parasite reservoir, the threat of Plasmodium vivax and Plasmodium knowlesi, insecticide resistance in Anopheles vectors and outdoor malaria transmission. This book is one little step forward to bring together in 17 chapters the experiences of malaria-expert researchers from five continents to present updated information on disease epidemiology and control at the national/regional level, highlighting the constraints, challenges, accomplishments and prospects of malaria elimination.

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Malaria is one of the most important OC emergingOCO or OC resurgentOCO infectious diseases. According to the World Health Organization, this mosquito-borne infection is a leading cause of suffering, death, poverty, and underdevelopment in the world today. Every year 500 million people become severely ill from malaria and more than a million people die, the great majority of them women and children living in sub-Saharan Africa. In 2008, it was estimated, a child would die of the disease every thirty seconds, making malaria OCo together with HIV/AIDS and tuberculosis OCo a global public health emergency. This is in stark contrast to the heady visions of the 1950s predicting complete global eradication of the ancient scourge. What went wrong?. This question warrants a closer look at not just the disease itself, but its long history and the multitude of strategies to combat its spread. This book collects the many important milestones in malaria control and treatment in one convenient volume. Importantly, it also traces the history of the disease from the 1920s to the present, and over several continents. It is the first multidisciplinary volume of its kind combining historical and scientific information that addresses the global challenge of malaria control. Malaria remains as resurgent as ever and The Global Challenge of Malaria: Past Lessons and Future Prospects will examine this challenge OCo and the range of strategies and tools to confront it OCo from an interdisciplinary and transnational perspective. Contents: Lessons of History: Malaria in America (Margaret Humphreys); Technological Solutions: The Rockefeller Insecticidal Approach to Malaria Control, 1920OCo1950 (Darwin H Stapleton); Malaria Control and Eradication Projects in Tropical Africa, 1945OCo1965 (James L A Webb, Jr); The Use and Misuse of History: Lessons from Sardinia (Frank M Snowden); Popular Education and Participation in Malaria Control: A Historical Overview (Socrates Litsios); Scientific, Medical, and Public Health Perspectives: The Contribution of the Gambia to Malaria Research (Brian Greenwood); InsecticideOCoTreated Bednets and Malaria Control: Strategies, Implementation, and Outcome (Harry V Flaster, Emily Mosites, and Brian G Blackburn); The Scientific and Medical Challenge of Malaria (Tiffany Sun and Richard Bucala). Readership: Historians of medicine; research scientists; clinicians, especially in the specialties of tropical medicine and infectious diseases; public health officials; environmentalists; and students in public health and history of medicine programs; general readers interested in contemporary issues of global health."