How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine. Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have not yet been able to replicate the heart’s perfect engineering. But, as Sian Harding shows us in The Exquisite Machine, new scientific developments are opening up the mysteries of the heart. And this explosion of new science—ultrafast imaging, gene editing, stem cells, artificial intelligence, and advanced sub-light microscopy—has crucial, real-world consequences for health and well-being. Harding—a world leader in cardiac research—explores the relation between the emotions and heart function, reporting that the heart not only responds to our emotions, it creates them as well. The condition known as Broken Heart Syndrome, for example, is a real disorder than can follow bereavement or stress. The Exquisite Machine describes the evolutionary forces that have shaped the heart’s response to damage, the astonishing rejuvenating power of stem cells, how we can avoid heart disease, and why it can be so hard to repair a damaged heart. It tells the stories of patients who have had the devastating experiences of a heart attack, chaotic heart rhythms, or stress-induced acute heart failure. And it describes how cutting-edge technologies are enabling experiments and clinical trials that will lead us to new solutions to the worldwide scourge of heart disease.

An anecdotal lifestyle guide for fans of French and English culture shares tips for inexpensively enjoying everything from travel and fashion to gardening and dining, in a reference inspired by 16th-century exotic encyclopedias that includes coverage of such esoteric topics as the history of champagne and Julia Child's secret to a perfect omelet.

The bestselling author of Intern and Doctored tells the story of the thing that makes us tick For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As the cardiologist and bestselling author Sandeep Jauhar shows in Heart: A History, it was only recently that we demolished age-old taboos and devised the transformative procedures that have changed the way we live. Deftly alternating between key historical episodes and his own work, Jauhar tells the colorful and little-known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ. He introduces us to Daniel Hale Williams, the African American doctor who performed the world’s first open heart surgery in Gilded Age Chicago. We meet C. Walton Lillehei, who connected a patient’s circulatory system to a healthy donor’s, paving the way for the heart-lung machine. And we encounter Wilson Greatbatch, who saved millions by inventing the pacemaker—by accident. Jauhar deftly braids these tales of discovery, hubris, and sorrow with moving accounts of his family’s history of heart ailments and the patients he’s treated over many years. He also confronts the limits of medical technology, arguing that future progress will depend more on how we choose to live than on the devices we invent. Affecting, engaging, and beautifully written, Heart: A History takes the full measure of the only organ that can move itself.

Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. People are essentially giant assemblies of interacting nanoscale machines.

Show how to produce incredibly beautiful seascapes. Using threads as an artist would use paints to achieve stunningly realistic pictures full of mood and atmosphere - waves crashing onto a windswept beach, sunlight sparkling on a bright blue Mediterranean sea and dramatic sunset skies -- all created using just two simple machine stitches.--Cover.

With a New Introduction by Jaron Lanier A Salon Best Book of the Year In 1997, the computer was still a relatively new tool---a sleek and unforgiving machine that was beyond the grasp of most users. With intimate and unflinching detail, software engineer Ellen Ullman examines the strange ecstasy of being at the forefront of the predominantly male technological revolution, and the difficulty of translating the inherent messiness of human life into artful and efficient code. Close to the Machine is an elegant and revelatory mediation on the dawn of the digital era.