Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

The Impossible reveals prayer's immediate and powerful impact through the true account of a family whose son died and was miraculously resurrected. Through the years and the struggles, when life seemed more about hurt and loss than hope and mercy, God was positioning the Smiths for something extraordinary-the death and resurrection of their son. When Joyce Smith's fourteen-year-old son John fell through an icy Missouri lake one winter morning, she and her family had seemingly lost everything. At the hospital, John lay lifeless for more than sixty minutes. But Joyce was not ready to give up on her son. She mustered all her faith and strength into one force and cried out to God in a loud voice to save him. Miraculously, her son's heart immediately started beating again. In the coming days, John would defy every expert, every case history, and every scientific prediction. Sixteen days after falling through the ice and being clinically dead for an hour, he walked out of the hospital under his own power, completely healed. The Impossible is about a profound truth: prayer really does work. God uses it to remind us that He is always with us, and when we combine it with unshakable faith, nothing is impossible.

In The Breakthrough, veteran journalist Gwen Ifill surveys the American political landscape, shedding new light on the impact of Barack Obama’s stunning presidential victory and introducing the emerging young African American politicians forging a bold new path to political power. Ifill argues that the Black political structure formed during the Civil Rights movement is giving way to a generation of men and women who are the direct beneficiaries of the struggles of the 1960s. She offers incisive, detailed profiles of such prominent leaders as Newark Mayor Cory Booker, Massachusetts Governor Deval Patrick, and U.S. Congressman Artur Davis of Alabama (all interviewed for this book), and also covers numerous up-and-coming figures from across the nation. Drawing on exclusive interviews with power brokers such as President Obama, former Secretary of State Colin Powell, Vernon Jordan, the Reverend Jesse Jackson, his son Congressman Jesse Jackson Jr., and many others, as well as her own razor-sharp observations and analysis of such issues as generational conflict, the race/ gender clash, and the "black enough" conundrum, Ifill shows why this is a pivotal moment in American history. The Breakthrough is a remarkable look at contemporary politics and an essential foundation for understanding the future of American democracy in the age of Obama.

Breakthrough: Trusting God for Big Change in Your Church encourages leaders of churches that are struggling and wondering if it's time to close the doors on God's work through them, their family, their church, or their ministry. This book is especially for those who have the audacity to dare to imagine where a new window might open as an old door is closing. Breakthrough reveals gritty, well-grounded hope around every corner.

"A clear and insightful look at why teaching must be conceived as constant learning about learning. The analysis of past failed reforms and the general conditions needed for success is well-stated and illuminating." —Grant Wiggins Authentic Education Redesign classroom instruction to transform learning for both students and teachers! Breakthrough presents a revolutionary new approach to educational reform, breaking away from the conventional paradigm to help educators create focused instruction, transform the classroom experience, and dramatically raise—and sustain—performance levels for students and teachers alike. This book provides the breakthrough concepts needed for developing precise, validated, data-driven instruction personalized to each and every student. Synthesizing the best of current instructional models, this framework focuses on the components of the Triple P Breakthrough Model: Personalization—meaningful, student-centered classroom interactions; Precision—using formative assessments to monitor individual student progress; and Professional Learning—daily, ongoing learning for all educators. Helping educators create expert instructional systems while breaking through the "prescription trap," the authors introduce unique elements of the Breakthrough model, including: Improvement by design Assessment for learning Critical learning instructional paths Mapping instructional paths Smart use of data to drive instruction Locking in ongoing improvement Breakthrough establishes the tipping point for moving toward personalized, high-quality instruction and learning in the classroom to ensure continuous improvement and ongoing academic success.

Publisher description

As the youngest bureau chief and head of the Chicago Police Department's Major Case Squad, Boone Drake seems to have it all under control. Only those closest to him know that just a few short years ago, he lost everything that mattered to him in a tragic accident. After years of healing, his life is back on track. He recently married a wonderful woman named Haeley, adopted her son, bought a beautiful home, and rediscovered his faith. But Boone can't fight the feeling that something is about to go terribly wrong . . . again. When an all-too-personal case takes Boone to Beijing at a time when Haeley can least afford to let him go, Boone is forced to make a difficult choice. There he becomes enmeshed in a dangerous human-trafficking ring that takes him through the famed Hutong District's narrow streets, alleys, and hovels. Teamed with a former Liberation Army officer, Boone has one chance to pull off an elaborate sting and rescue a young boy before he disappears forever.