Symptomatic: The Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders offers a novel approach structured around the panoply of 75 symptoms with which a person with Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD) may present to a clinician. The content is arranged intuitively from head to feet, with each chapter integrating clinical case studies with a concise discussion and two important diagnostic tools: a simplified algorithm for diagnosing and treating each symptom and differential diagnoses and alternative explanations for their symptoms. This is a handbook that combines the expertise of some 70 leading clinicians, representing more than 30 specialties. This book is suited for clinicians who need a concise and straight-forward presentation of the various and complex symptoms they confront in their clinical practice. It brings forth a field of knowledge emerging from interdisciplinary collaboration despite the pressures of specialization that bridges gaps in understanding between the several dozen disciplines implicated in EDS and HSD. • A comprehensive compendium of the symptoms of EDS and HSD to aid clinicians and patients • Symptom-based chapters for ease of making a diagnosis • A case report, differential diagnosis, discussion, and diagnostic and treatment algorithm for each symptom

In the period just prior to medicine's modernity—before the rise of Renaissance anatomy, the centralized regulation of medical practice, and the valorization of scientific empiricism—England was the scene of a remarkable upsurge in medical writing. Between the arrival of the Black Death in 1348 and the emergence of printed English books a century and a quarter later, thousands of discrete medical texts were copied, translated, and composed, largely for readers outside universities. These widely varied texts shared a model of a universe crisscrossed with physical forces and a picture of the human body as a changeable, composite thing, tuned materially to the world's vicissitudes. According to Julie Orlemanski, when writers like Geoffrey Chaucer, Robert Henryson, Thomas Hoccleve, and Margery Kempe drew on the discourse of phisik—the language of humors and complexions, leprous pustules and love sickness, regimen and pharmacopeia—they did so to chart new circuits of legibility between physiology and personhood. Orlemanski explores the texts of her vernacular writers to show how they deployed the rich terminology of embodiment and its ailments to portray symptomatic figures who struggled to control both their bodies and the interpretations that gave their bodies meaning. As medical paradigms mingled with penitential, miraculous, and socially symbolic systems, these texts demanded that a growing number of readers negotiate the conflicting claims of material causation, intentional action, and divine power. Examining both the medical writings of late medieval England and the narrative and poetic works that responded to them, Symptomatic Subjects illuminates the period's conflicts over who had the authority to construe bodily signs and what embodiment could be made to mean.

Nobody said life would be easy, and it hasnt been for Philippa Sue Richardson. In 2012, she moved to Melbourne, Australia, where her life altered greatly, changed for the betterbut it took some time to get there. Through struggles with physical and mental health, Philippa prevailed and found a way to live a life of gratitude. Symptomatic Addict is Philippas way of reaching out to the world, sharing her thoughts moment by moment. Her words take all forms, from recipes to poems to sudden self-actualizing epiphanies. She truly and fearlessly expresses herself through her experiences, adventures, and innermost thoughts. In order to find peace, Philippa believes a person must first find respect and thankfulness. Every unforeseen trial and tribulation has meaning, and with thankfulness, it is possible to embrace even the darkest of times. In life, few things are what they seem, but everything serves its purpose if only we slow down, observe, and enjoy.

The WHO global health sector strategy on sexually transmitted infections, 2016–2021, endorsed by the World Health Assembly in 2016, aims to eliminate STIs as a public health threat by 2030. In 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis. Recent changes in the epidemiology of STIs and progress in prevention, diagnosis and treatment of STIs and HIV have necessitated changes in approaches to STI prevention and management. To address these STIs, the most widely used approach in clinical settings is the syndromic management of STIs. In most resource-limited settings, the syndromic management flow charts are still the standard of care where laboratory diagnosis is not available or is hard to access. The objectives of these guidelines are to provide updated, evidence-informed clinical and practical recommendations on the case management of people with symptoms of STIs; and to support countries in updating their national guidelines for the case management of people with symptoms of STIs. These guidelines include the management of symptomatic infections related to urethral discharge syndrome, including persistent urethral discharge syndrome; vaginal discharge syndrome, including persistent vaginal discharge; anorectal infection; genital ulcer disease syndrome; and lower abdominal pain syndrome. These guidelines are intended for programme managers for STI prevention and control at the national level and the health-care providers at the frontline – primary, secondary and tertiary health care.