Toxicokinetics in Risk Assessment discusses the noncancer risk assessment process and its reliance on uncertainty factors in order to facilitate the continued study and refinement of the scientific basis for health risk assessment. This text clearly demonstrates the application of physiologically-based pharmacokinetic (PBPK) modeling in human healt

Written by experts in the field, this important book provides anintroduction to current risk assessment practices and proceduresand explores the intrinsic complexities, challenges, andcontroversies associated with analysis of environmental healthrisks. Environmental Health Risk Assessment for Public Healthoffers 27 substantial chapters on risk-related topics thatinclude: What Is Risk and Why Study Risk Assessment The Risk Assessment–Risk Management Paradigm Risk Assessment and Regulatory Decision-Making in EnvironmentalHealth Toxicological Basis of Risk Assessment The Application of PBPK Modeling to Risk Assessment Probabilistic Models to Characterize Aggregate and CumulativeRisk Molecular Basis of Risk Assessment Comparative Risk Assessment Occupational Risk Radiological Risk Assessment Microbial Risk Assessment Children’s Risk Assessment Life Cycle Risk Environmental Laws and Regulations Precautionary Principles Risk Communication

This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for study design in mixture toxicology. While no extensive prior knowledge or toxicological experience is required, the practice-oriented case studies and examples in the second part make this the ideal companion for the professional toxicologist in industry or healthcare institutions with little time for academic study.