Chapter 1 contains an Introduction to the role of metal complexes in functional assemblies. The remainder of the chapter is devoted to an Introduction to the "sarcophagine" class of ligands, including their synthesis, stereochemistry and electrochemical properties. Chapter 2 describes the synthesis of a variety of alkylated derivatives of the cage amines "diaminosarcophagine" and "aminomethylsarcophagine". Procedures have been developed for the selective functionalisation of the primary amine sites through protection of the secondary amines by coordination to a metal ion. Experiments with the Cu(II) complex of diaminosarcophagine indicated mono-, di-, and tri-alkylation were possible by varying the reaction conditions but separation of the various alkylation products was extremely difficult. Methods were developed, therefore, to prepare the desired di-alkylated products in a selective manner which overcame the need for difficult and tedious separations. A method for the isolation of the free aminomethylsarcophagine ligand in good yields was developed. Copper and magnesium complexes of this ligand were prepared, which allowed the selective synthesis of monoalkylated cages. Magnesium(II) complexes were employed to successfully protect the secondary amines, and allowed the ready removal of the metal ion from the cage to give the free alkylated ligands. These ligands could then be used to prepare a variety of metal complexes containing one or two alkyl groups. Chapter 3 describes attempts to prepare thermotropic metallomesogens (liquid crystals) of a variety of cage complexes. The simple mono- and di-alkylated compounds described in Chapter 2 were shown not to form thermotropic LC phases and new complexes containing three and six alkyl groups were prepared in the hope of producing mesogenic behaviour. None of the compounds synthesised exhibited thermotropic liquid crystalline phases but the aqueous solution behaviour of the triple tailed complexes displayed interesting phenomena, most notably the production of viscoelastic solutions at ≤ 1 wt%. This behaviour was shown, in the case of the Co(III) complex, to be due to the presence of long cylindrical or "wormlike" micelles in pure water, which can be readily converted to vesicle structures. The electrochemical behaviour of the Co(III) complex displayed some interesting adsorption behaviour at a hydrophobic electrode surface giving an immobilised film. Chapter 4 describes the synthesis and characterisation of a series of Co(III) complexes linked by short peptide-like disulfide spacers. The solution electrochemical characteristics of the new complexes is reported. Two immobilisation methods, namely electrodeposition and traditional "self-assembly", were investigated for the preparation of monolayers of the disulfides on gold surfaces and both were found to give indistinguishable equilibrium surface coverages and electrochemical characteristics. An initial induction period was observed, most evident for the electrodeposited films, and this phenomenon has been tentatively assigned as due to a surface rearrangement effect.

This fundamental book presents the most comprehensive summary of the current state in chemistry of cage metal complexes. After their previous book “The Encapsulation Phenomenon” (www.springer.com/978-3-319-27737-0) the authors in this book focus on the encapsulation of metal ions by different types of three-dimensional mono- and polynucleating caging ligands. Within these cage metal complexes, (metal) ions can be isolated from external factors. The book provides both a classification of the cage compounds and summaries of synthetic approaches. On that basis the authors then describe the unique chemical and physical properties and the resulting reactivity of the cage compounds, as well as practical and potential applications as potent topological drugs and prodrugs, antifibrillogenic agents, radiodiagnostic and radiotherapeutic compounds, paramagnetic probes, single-molecule magnets, electrocatalysts for hydrogen production, (photo)electronic devices, and many more. Readers will find a well-structured and concise overview, with particular emphasis on a review of synthesis and reactivity of various cage metal complexes, summarizing over 400 literature references, clearly presented in over 300 color schemes and figures.

Photophysical and Photochemical Properties of Aromatic Compounds is the first book to collect and classify all available quantitative data on the photochemistry and luminescence of aromatic compounds. Compounds are classified by both spectral-luminescent (e.g., extinction coefficients, energies and lifetimes of lower excited states) and photochemical properties. In addition, all of the quantum yields available have been collected. The variety of photochemical reactions of aromatics is examined based on eight types of elementary monomolecular and bimolecular photochemical processes. Aromatic compounds are grouped into eight categories, and the book analyzes the possibilities of occurrence of all types of elementary photoprocesses.

Issues in Specialized Chemical and Chemistry Topics: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Specialized Chemical and Chemistry Topics. The editors have built Issues in Specialized Chemical and Chemistry Topics: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Specialized Chemical and Chemistry Topics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Specialized Chemical and Chemistry Topics: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Sets the stage for the design and application of new protein cages Featuring contributions from a team of international experts in the coordination chemistry of biological systems, this book enables readers to understand and take advantage of the fascinating internal molecular environment of protein cages. With the aid of modern organic and polymer techniques, the authors explain step by step how to design and construct a variety of protein cages. Moreover, the authors describe current applications of protein cages, setting the foundation for the development of new applications in biology, nanotechnology, synthetic chemistry, and other disciplines. Based on a thorough review of the literature as well as the authors' own laboratory experience, Coordination Chemistry in Protein Cages Sets forth the principles of coordination reactions in natural protein cages Details the fundamental design of coordination sites of small artificial metalloproteins as the basis for protein cage design Describes the supramolecular design and assembly of protein cages for or by metal coordination Examines the latest applications of protein cages in biology and nanotechnology Describes the principles of coordination chemistry that govern self-assembly of synthetic cage-like molecules Chapters are filled with detailed figures to help readers understand the complex structure, design, and application of protein cages. Extensive references at the end of each chapter serve as a gateway to important original research studies and reviews in the field. With its detailed review of basic principles, design, and applications, Coordination Chemistry in Protein Cages is recommended for investigators working in biological inorganic chemistry, biological organic chemistry, and nanoscience.