Studies of Dentin Matrix Protein 1 (DMP1) Regulation and Function in Vivo
Title | Studies of Dentin Matrix Protein 1 (DMP1) Regulation and Function in Vivo PDF eBook |
Author | Yongbo Lu |
Publisher | |
Pages | 124 |
Release | 2007 |
Genre | Bone cells |
ISBN | 9780549000600 |
Dentin matrix protein 1 (DMP1) is a highly phosphorylated extracellular matrix protein, predominantly expressed in osteocytes in bone. Full-length DMP1 is enzymatically processed into a 37 kDa N- and a 57 kDa C-terminal fragment in vivo. The goal of this study was to identify the cis-regulatory regions that control osteoctye-specific expression of the DMP1 gene, to determine the in vivo function of the 57 kDa C-terminal fragment and to determine the role of DMP1 in control of phosphate homeostasis.
Studies of Mouse Dentin Matrix Protein One Gene Regulation in Vitro and in Vivo
Title | Studies of Mouse Dentin Matrix Protein One Gene Regulation in Vitro and in Vivo PDF eBook |
Author | Dayong Guo |
Publisher | |
Pages | 104 |
Release | 2001 |
Genre | |
ISBN |
Studies of Dentin Matrix Protein 1 (DMP1) Cis-DNA Regulatory Regions in an Osteoblast-osteocyte Differentiation Model and Gene Expression Profile Comparisons Between 2T3 Osteoblasts and MLO-Y4 Osteocyte-like Cells
Title | Studies of Dentin Matrix Protein 1 (DMP1) Cis-DNA Regulatory Regions in an Osteoblast-osteocyte Differentiation Model and Gene Expression Profile Comparisons Between 2T3 Osteoblasts and MLO-Y4 Osteocyte-like Cells PDF eBook |
Author | Wuchen Yang |
Publisher | |
Pages | 252 |
Release | 2003 |
Genre | Bone cells |
ISBN |
Phosphorylated Extracellular Matrix Proteins of Bone and Dentin
Title | Phosphorylated Extracellular Matrix Proteins of Bone and Dentin PDF eBook |
Author | Michel Goldberg |
Publisher | Bentham Science Publishers |
Pages | 464 |
Release | 2012-09-11 |
Genre | Medical |
ISBN | 1608054659 |
Phosphorylated Extracellular Matrix Proteins of Bone and Dentin is the second volume of the e-book series Frontiers between Science and Clinic in Odontology. The phosphorylated proteins of the extracellular matrix of bone and teeth play a crucial structural role in the two tissues. They also act as signaling molecules. Phosphorylated extracellular matrix proteins have been implicated in nucleation and mineralization of skeletal tissues. This e-book covers research on these specific proteins, including details about the cells producing these molecules, their impact on bone and teeth pathology (osteogenesis and dentinogenesis imperfecta) and the potential of these molecules in promoting of inhibiting mineralization. This e-book also explains processes under the control of some enzymes - TNAP and metalloproteases (MMPs) - such as intracellular regulation in bone and dentine, splicing, respective roles of cleavage products, SIBLINGs, nucleation and crystal growth and regulation. This second volume serves as a valuable reference to practicing odontologists, biology and biomaterials scientists and tissue engineers interested in protein research related to tooth and bone formation.
In Vivo Role of Dentin Matrix Protein 1 in Cytodifferentiation of Dental Pulp Stem Cells
Title | In Vivo Role of Dentin Matrix Protein 1 in Cytodifferentiation of Dental Pulp Stem Cells PDF eBook |
Author | Abdullah S. Almushayt |
Publisher | |
Pages | 246 |
Release | 2002 |
Genre | |
ISBN |
Mimicking the Extracellular Matrix
Title | Mimicking the Extracellular Matrix PDF eBook |
Author | Gregory H. Hudalla |
Publisher | Royal Society of Chemistry |
Pages | 422 |
Release | 2015-11-18 |
Genre | Medical |
ISBN | 1849738335 |
Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.
Extracellular Matrix Assembly and Structure
Title | Extracellular Matrix Assembly and Structure PDF eBook |
Author | Peter D. Yurchenco |
Publisher | Academic Press |
Pages | 483 |
Release | 2013-10-22 |
Genre | Science |
ISBN | 1483289427 |
The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Addresses assembly of most of the known classes of extracellular matrix macromolecules Discusses higher order structures produced by ECM Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling