Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Although the disease is not very often, every otorhinolaryngologist will experience some patients suffering from vocal fold paralysis. This is the first and unique book solely devoted to this topic. Offers step-by-step descriptions and evaluations of the materials and/or methods of well-established techniques and new therapeutic options and approaches. Written by leading experts: Blitzer is speaker of the American Academy of Otorhinolaryngology and Head and Neck Surgery (AAO-HNS); Sulica, also a speaker of the AAO-HNS, works in his department. Vocal Fold Paralysis is a clinically useful reference for evaluation and treatment, as well as a summary of current knowledge and investigational approaches.

Sleep Paralysis: Historical, Psychological, and Medical Perspectives offers the first comprehensive examination of sleep paralysis from both clinical and cultural perspectives. Dr. Brian Sharpless and Dr. Karl Doghramji provide a thorough and easily readable resource on the phenomenon and present differential diagnosis suggestions, medication guidance, and a new treatment approach for mental health professionals.

Experienced by millions as supernatural assault, isolated sleep paralysis (ISP) feels like being awake and aware in bed as someone - or something - holds you down. These sensations are sometimes accompanied by frightening and realistic hallucinations. In this book these encounters with ghosts, vampires - and even succubi - are honored afresh from the perspective of contemporary dream science. Although terrifying, ISP visions can also be a reliable portal to other extraordinary states, including lucid dreaming, out-of-body experiences and otherworldly journeys.

Sleep Paralysis explores a distinctive form of nocturnal fright: the "night-mare," or incubus. In its original meaning a night-mare was the nocturnal visit of an evil being that threatened to press the life out of its victim. Today, it is known as sleep paralysis-a state of consciousness between sleep and wakefulness, when you are unable to move or speak and may experience vivid and often frightening hallucinations. Culture, history, and biology intersect to produce this terrifying sleep phenomenon. Although a relatively common experience across cultures, it is rarely recognized or understood in the contemporary United States. Shelley R. Adler's fifteen years of field and archival research focus on the ways in which night-mare attacks have been experienced and interpreted throughout history and across cultures and how, in a unique example of the effect of nocebo (placebo's evil twin), the combination of meaning and biology may result in sudden nocturnal death.

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

The first book to put the physical symptoms of stress in their historical and cultural context. This fascinating history of psychosomatic disorders shows how patients throughout the centuries have produced symptoms in tandem with the cultural shifts of the larger society. Newly popularized diseases such as "chronic fatigue syndrome" and "total allergy syndrome" are only the most recent examples of patients complaining of ailments that express the truths about the culture in which they live.