James Reynolds was born in England ca. 1620. He and his wife, Deborah, had seven children, all probably born in Plymouth Colony. He died at North Kingstown, Rhode Island, in 1700. Follett Reynolds, a descendant and the son of Deacon William Reynolds, was born at Pownall, Vermont, in 1789. He married Hannah Holmes at Cambridge, Vermont, in 1813. They had six children. He died at Cambridge in 1854. Descendants lived in Vermont, Wisconsin, Kansas, Illinois, and elsewhere.

James Reynolds was probably born in the 1620s in England. He married Deborah in about 1647, probably in Plymouth Colony, Massachusetts. They had eight children. James died in 1700 in North Kingstown, Rhode Island. Descendants and relatives lived in Rhode Island, Massachusetts, Illinois, Nebraska, Wisconsin, Minnesota and elsewhere.