Sleep and Aging provides a unique and timely collection of review articles that cover the gamut of basic and clinical aspects of sleep and the abnormalities in sleep associated with aging and neurological disorders that occur during aging. From the evolutionary basis of sleep and its normal functions in processes such as learning and memory, to considerations of the roles of sleep abnormalities in neurological disorders such as depression, Alzheimer's and Parkinson's diseases, the chapters are written by experts in the field. Several chapters focus on signalling pathways involved in sleep regulation and abnormalities in sleep, including those activated by serotonin and BDNF. Basic and clinical research on insomnia, sleep apnea and other disorders of sleep, are covered thus providing students and scientists at all levels with a valuable source of information to advance their understanding of this important topic in aging, biology and medicine. The circuits in the brain involved in sleep regulation, their neurochemistry, how they are altered in disorders of sleep and current clinical treatments of various sleep disorders are reviewed. The important role of sleep disturbances in neurodegenerative disorders is described and research in this particular area is leading to a better understanding of the relationships between synaptic plasticity, neuronal degeneration and the clinical manifestations of disorders such as Alzheimer's disease, Parkinson's disease and depression. This book is a must for scientists, as well as non-scientists, who are interested in the neurobiology of aging, sleep and neurodegenerative disorders.

Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

Foundations of Sleep Health presents sleep health as a critical element of overall individual and population health. Sleep disorders are an increasing problem plaguing more than 40 million Americans. Sleep impacts numerous biological functions and plays a critical role in brain development, including learning and memory consolidation, cognitive functioning, and emotion regulation. This book provides an historic and current overview of the state of sleep health with an emphasis on the interplay between several levels of determinants and factors that influence sleep health. The text provides students in the health professions with in-depth discussion on the theory, research, and practice of sleep health, while also detailing mechanisms, hypotheses, and determinants of sleep and ways to improve sleep health. - Discusses the current state of knowledge of sleep health, research into the factors that contribute to and are impacted by sleep health - Uses a socioecological model to examine the whole range of determinants of sleep health, from biological to upstream environmental factors and possible modes of intervention - Contains a detailed glossary of sleep health terms to aid in the understanding of key concepts - Includes learning outcomes for each chapter, objective assessments of knowledge, with explanations, and open-ended questions designed to facilitate discussion

Sleep is considered one of the vital signs and has become an important public health issue in our society. Thus, sleep impacts on overall health and, conversely, certain common medical conditions can impair sleep. Emerging evidence, in conjunction with clinical experience, demonstrates that physical therapy improves several sleep disorders and also optimized sleep contributes to boost rehabilitation. As health care professionals, physical therapists are singularly concerned with well-being and need to be competent to instruct their patients to rest and sleep. This book discusses evidences of physiotherapy and sleep medicine. It elucidates the neurophysiological background and mechanisms for physiotherapeutic resources and techniques, directing the future for promising research in the area. Divided in seven sections, the work initially addresses the basic concepts of sleep and physiotherapy and its relation to practice, including the importance of sleep medicine for health. The second section focuses on the basic conceptions of physical therapists' understanding and working in clinical practice and research with sleep.The next section reviews the most common sleep disturbances such as insomnia, restless legs syndrome, and respiratory sleep disturbances. Special populations, spotlighting childhood and adolescence, women physiologic reproductive stages, sleep and gender, and sleep and pain interactions are also examined. Last sections discuss the physical therapy resources to improve sleep and to treat sleep disturbances. This title is an essential resource not only for graduate students, residents, health professionals and physiotherapists working in prevention and rehabilitation, but also for researchers interested in screening, diagnostic and treatment innovations. It is addressed to neurologists, sleep medicine specialists and physical educators as well.

Until very recently, our knowledge about the neural basis of cognitive aging was based on two disciplines that had very little contact with each other. Whereas the neuroscience of aging investigated the effects of aging on the brain independently of age-related changes in cognition, the cognitive psychology of aging investigated the effects of aging on cognition independently of age-related changes in the brain. The lack of communication between these two disciplines is currently being addressed by an increasing number of studies that focus on the relationships between cognitive aging and cerebral aging. This rapidly growing body of research has come to constitute a new discipline, which may be called cognitive neuroscience of aging. The goal of Cognitive Neuroscience of Aging is to introduce the reader to this new discipline at a level that is useful to both professionals and students in the domains of cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology, neurology, and other, related areas. This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging on neural activity during different cognitive functions, including perception and attention, imagery, working memory, long-term memory, and prospective memory. The third section focuses on clinical and applied topics, such as the distinction between healthy aging and Alzheimers disease and the use of cognitive training to ameliorate age-related cognitive decline. The last section describes theories that relate cognitive and cerebral aging, including models accounting for functional neuroimaging evidence and models supported by computer simulations. Taken together, the chapters in this volume provide the first unified and comprehensive overview of the new discipline of cognitive neuroscience of aging.