The life and career of Mr. Sherlock Holmes haves inspired the interest of many of the brightest intellects in the world. They have expended great efforts to penetrate beyond the glimpses afforded us in the 60 published adventures - to detect the real underlying character of "the best and the wisest man" Dr. Watson has ever known ("The Final Problem" by A. C. Doyle). To the hundreds of past and present day Sherlockians, Holmesians, Doyeleans, we owe a great deal of gratitude for helping to shred the veil which has been created to obfuscate the real character of our remarkable hero: from the sainted Christopher Morley and Vincent Starrett; to the renowned commentators Ronald A. Knox, William S. Baring-Gould, Edgar W. Smith, Sydney C. Roberts, Michael Harrison, Michael Hardwick, and many others too numerous to mention. Commentators have included bookmen, journalists and essayists, physicians, psychiatrists and pathologists, chemists, monsignors and vicars, barristers and solicitors, and automobile executives. All have brought their intelligence, unique perspectives, and, most of all, a very desperate need for knowledge to this quest, their labor of love. With great humility but stout heart, I feel highly motivated, even obligated, to attempt to add my voice to this ongoing effort. As a microbiologist, I hope to bring a different perspective to these studies. I am used to dealing with very minute objects that produce consequences much greater than their size would indicate. Is not this obsession with minutiae the perfect training and background for one who feels the need to participate in Sherlockian studies? I do hope that this makes me somewhat qualified to join in this important area of scholarly research.

This open access book considers science and empire, and the stories we tell ourselves about them. Using British Nobel laureate Ronald Ross (1857-1932) and his colleagues as access points to a wider professional culture, Empire Under the Microscope explores the cultural history of parasitology and its relationships with the literary and historical imagination between 1885 and 1935. Emilie Taylor-Pirie examines a wealth of archival material including medical lectures, scientific publications, popular biography, and personal and professional correspondence, alongside novels, poems, newspaper articles, and political speeches, to excavate the shared vocabularies of literature and medicine. She demonstrates how forms such as poetry and biography; genres such as imperial romance and detective fiction; and modes such as adventure and the Gothic, together informed how tropical diseases, their parasites, and their vectors, were understood in relation to race, gender, and nation. From Ancient Greece, to King Arthur’s Knights, to the detective work of Sherlock Holmes, parasitologists manipulated literary and historical forms of knowledge in their professional self-fashioning to create a modern mythology that has a visible legacy in relationships between science and society today.

The riveting history of tuberculosis, the world’s most lethal disease, the two men whose lives it tragically intertwined, and the birth of medical science. In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing. When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s “remedy” was either sloppy science or outright fraud. But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes. Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

Was Sherlock Holmes really a woman?

The 21st century is a good time to be Sherlock Holmes. He stars in the Guy Ritchie films, with Robert Downey, Jr.; an internationally popular BBC television series featuring Benedict Cumberbatch; a novel sanctioned by the Arthur Conan Doyle Estate; and dozens of additional novels and short stories, including two by Neil Gaiman. Add to this the videogames, comic books, and fan-created works, plus a potent Internet and social media presence. Holmes' London has become a prime destination for cinematic tourists. The evidence is clearly laid out in this collection of 14 new essays: Holmes and Watson are more popular than ever. The detective has been portrayed as hero, and antihero. He's tech savvy, and scientifically detached--even psychologically aberrant. He has been romantically linked to The Woman and bromantically to Watson. Whether Victorian or modern, he continues to fascinate. These essays explain why he is destined to be with us for years to come. Instructors considering this book for use in a course may request an examination copy here.

' Kate Winkler Dawson is an unbelievable crime historian and such a talented storyteller. ' Karen Kilgariff, cohost of the My Favorite Murder podcast 'Heinrich changed criminal investigations forever, and anyone fascinated by the myriad detective series and TV shows about forensics will want to read [this].' The Washington Post 'An entertaining, absorbing combination of biography and true crime.' Kirkus ' Kate Winkler Dawson has researched both her subject and his cases so meticulously that her reconstructions and descriptions made me feel part of the action rather than just a reader and bystander. She has brought to life Edward Oscar Heinrich's character, determination, and skill so vividly that one is left bemused that this man is so little known to most of us. ' Patricia Wiltshire, author of Traces and The Nature of Life and Death Berkeley, California, 1933. In a lab filled with curiosities – beakers, microscopes, Bunsen burners and hundreds of books – sat an investigator who would go on to crack at least 2,000 cases in his 40-year career. Known as the 'American Sherlock Holmes', Edward Oscar Heinrich was one of the greatest – and first – forensic scientists, with an uncanny knack for finding clues, establishing evidence and deducing answers with a skill that seemed almost supernatural. Based on years of research and thousands of never-before-published primary source materials, American Sherlock is a true-crime account capturing the life of the man who spearheaded the invention of a myriad of new forensic tools, including blood-spatter analysis, ballistics, lie-detector tests and the use of fingerprints as courtroom evidence.

"A young girl who is empowered, capable, and smart...the Enola Holmes book series convey an impactful message that you can do anything if you set your mind to it, and it does so in an exciting and adventurous way."--Millie Bobby Brown Enola Holmes is back! Nancy Springer's nationally bestselling series and breakout Netflix sensation returns to beguile readers young and old in Enola Holmes and the Black Barouche. Enola Holmes is the much younger sister of her more famous brothers, Sherlock and Mycroft. But she has all the wits, skills, and sleuthing inclinations of them both. At fifteen, she's an independent young woman--after all, her name spelled backwards reads 'alone'--and living on her own in London. When a young professional woman, Miss Letitia Glover, shows up on Sherlock's doorstep, desperate to learn more about the fate of her twin sister, it is Enola who steps up. It seems her sister, the former Felicity Glover, married the Earl of Dunhench and per a curt note from the Earl, has died. But Letitia Glover is convinced this isn't the truth, that she'd know--she'd feel--if her twin had died. The Earl's note is suspiciously vague and the death certificate is even more dubious, signed it seems by a John H. Watson, M.D. (who denies any knowledge of such). The only way forward is for Enola to go undercover--or so Enola decides at the vehement objection of her brother. And she soon finds out that this is not the first of the Earl's wives to die suddenly and vaguely--and that the secret to the fate of the missing Felicity is tied to a mysterious black barouche that arrived at the Earl's home in the middle of the night. To uncover the secrets held tightly within the Earl's hall, Enola is going to require help--from Sherlock, from the twin sister of the missing woman, and from an old friend, the young Viscount Tewkesbury, Marquess of Basilwether! Enola Holmes returns in her first adventure since the hit Netflix movie brought her back on the national bestseller lists, introducing a new generation to this beloved character and series.