Self-organization constitutes one of the most important theoretical debates in contemporary life sciences. The present book explores the relevance of the concept of self-organization and its impact on such scientific fields as: immunology, neurosciences, ecology and theories of evolution. Historical aspects of the issue are also broached. Intuitions relative to self-organization can be found in the works of such key western philosophical figures as Aristotle, Leibniz and Kant. Interacting with more recent authors and cybernetics, self-organization represents a notion in keeping with the modern world's discovery of radical complexity. The themes of teleology and emergence are analyzed by philosophers of sciences with regards to the issues of modelization and scientific explanation. The implications of self-organization for life sciences are here approached from an interdisciplinary angle, revealing the notion as already rewarding and full of promise for the future.

Self-organization constitutes one of the most important theoretical debates in contemporary life sciences. The present book explores the relevance of the concept of self-organization and its impact on such scientific fields as: immunology, neurosciences, ecology and theories of evolution. Historical aspects of the issue are also broached. Intuitions relative to self-organization can be found in the works of such key western philosophical figures as Aristotle, Leibniz and Kant. Interacting with more recent authors and cybernetics, self-organization represents a notion in keeping with the modern world's discovery of radical complexity. The themes of teleology and emergence are analyzed by philosophers of sciences with regards to the issues of modelization and scientific explanation. The implications of self-organization for life sciences are here approached from an interdisciplinary angle, revealing the notion as already rewarding and full of promise for the future.

Technological systems become organized by commands from outside, as when human intentions lead to the building of structures or machines. But many nat ural systems become structured by their own internal processes: these are the self organizing systems, and the emergence of order within them is a complex phe nomenon that intrigues scientists from all disciplines. Unfortunately, complexity is ill-defined. Global explanatory constructs, such as cybernetics or general sys tems theory, which were intended to cope with complexity, produced instead a grandiosity that has now, mercifully, run its course and died. Most of us have become wary of proposals for an "integrated, systems approach" to complex matters; yet we must come to grips with complexity some how. Now is a good time to reexamine complex systems to determine whether or not various scientific specialties can discover common principles or properties in them. If they do, then a fresh, multidisciplinary attack on the difficulties would be a valid scientific task. Believing that complexity is a proper scientific issue, and that self-organizing systems are the foremost example, R. Tomovic, Z. Damjanovic, and I arranged a conference (August 26-September 1, 1979) in Dubrovnik, Yugoslavia, to address self-organizing systems. We invited 30 participants from seven countries. Included were biologists, geologists, physicists, chemists, mathematicians, bio physicists, and control engineers. Participants were asked not to bring manu scripts, but, rather, to present positions on an assigned topic. Any writing would be done after the conference, when the writers could benefit from their experi ences there.

This book places everyday talk and role-modelling interactions at the forefront of an alternative change-leadership agenda, and introduces a number of practical approaches to help line managers and organizational specialists deliver this agenda more successfully. It is essential reading for organizational practitioners at all levels.

Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.

The synchronized flashing of fireflies at night. The spiraling patterns of an aggregating slime mold. The anastomosing network of army-ant trails. The coordinated movements of a school of fish. Researchers are finding in such patterns--phenomena that have fascinated naturalists for centuries--a fertile new approach to understanding biological systems: the study of self-organization. This book, a primer on self-organization in biological systems for students and other enthusiasts, introduces readers to the basic concepts and tools for studying self-organization and then examines numerous examples of self-organization in the natural world. Self-organization refers to diverse pattern formation processes in the physical and biological world, from sand grains assembling into rippled dunes to cells combining to create highly structured tissues to individual insects working to create sophisticated societies. What these diverse systems hold in common is the proximate means by which they acquire order and structure. In self-organizing systems, pattern at the global level emerges solely from interactions among lower-level components. Remarkably, even very complex structures result from the iteration of surprisingly simple behaviors performed by individuals relying on only local information. This striking conclusion suggests important lines of inquiry: To what degree is environmental rather than individual complexity responsible for group complexity? To what extent have widely differing organisms adopted similar, convergent strategies of pattern formation? How, specifically, has natural selection determined the rules governing interactions within biological systems? Broad in scope, thorough yet accessible, this book is a self-contained introduction to self-organization and complexity in biology--a field of study at the forefront of life sciences research.

The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.