The discovery in 2012 of the Higgs boson at the Large Hadron Collider (LHC) represents a milestone for the Standard Model (SM) of particle physics. Most of the SM Higgs production and decay rates have been measured at the LHC with increased precision. However, despite its experimental success, the SM is known to be only an effective manifestation of a more fundamental description of nature. The scientific research at the LHC is strongly focused on extending the SM by searching, directly or indirectly, for indications of New Physics. The extensive physics program requires increasingly advanced computational and algorithmic techniques. In the last decades, Machine Learning (ML) methods have made a prominent appearance in the field of particle physics, and promise to address many challenges faced by the LHC. This thesis presents the analysis that led to the observation of the SM Higgs boson decay into pairs of bottom quarks. The analysis exploits the production of a Higgs boson associated with a vector boson whose signatures enable efficient triggering and powerful background reduction. The main strategy to maximise the signal sensitivity is based on a multivariate approach. The analysis is performed on a dataset corresponding to a luminosity of 79.8/fb collected by the ATLAS experiment during Run-2 at a centre-of-mass energy of 13 TeV. An excess of events over the expected background is found with an observed (expected) significance of 4.9 (4.3) standard deviation. A combination with results from other \Hbb searches provides an observed (expected) significance of 5.4 (5.5). The corresponding ratio between the signal yield and the SM expectation is 1.01 +- 0.12 (stat.)+ 0.16-0.15(syst.). The 'observation' analysis was further extended to provide a finer interpretation of the V H(H → bb) signal measurement. The cross sections for the VH production times the H → bb branching ratio have been measured in exclusive regions of phase space. These measurements are used to search for possible deviations from the SM with an effective field theory approach, based on anomalous couplings of the Higgs boson. The results of the cross-section measurements, as well as the constraining of the operators that affect the couplings of the Higgs boson to the vector boson and the bottom quarks, have been documented and discussed in this thesis. This thesis also describes a novel technique for the fast simulation of the forward calorimeter response, based on similarity search methods. Such techniques constitute a branch of ML and include clustering and indexing methods that enable quick and efficient searches for vectors similar to each other. The new simulation approach provides optimal results in terms of detector resolution response and reduces the computational requirements of a standard particles simulation.

The absence of new physics at the TeV scale observed thus far at the Large Hadron Collider (LHC) motivates an increasing focus on searches for weakly-coupled new particles and exotic signatures. In particular, particles with macroscopic mean proper lifetimes, known as long-lived particles (LLPs), are of significant interest due to their ability to elude the majority of searches which rely on the assumption that Beyond Standard Model particles decay close to the primary interaction point. Many models which aim to solve various issues with the Standard Model (SM) introduce new particles with lifetimes that are either unconstrained, or even shown to prefer the macroscopic regime. These theories often point to the Higgs boson as a possible portal to new physics, with exotic Higgs decays being the primary phenomenological consequence and means of discovery. It is well motivated both from theory and experimental constraints to consider the scenario in which the particles produced in these exotic decays have macroscopic proper lifetimes and give rise to unique detector signatures. This work describes a search for exotic decays of the Higgs boson to two long-lived, neutral, spin-0 particles which subsequently decay to pairs of b quarks, giving the striking signature of displaced hadronic jets in the ATLAS inner detector. Several other ATLAS searches have probed this decay topology previously, excluding branching ratios of the Higgs boson to LLPs of more than 10% for proper lifetimes greater than 100mm. These searches relied on dedicated triggers designed to select events with LLPs decaying in the ATLAS calorimeter or muon spectrometer. The lack of an equivalent trigger for LLP decays in the ATLAS inner detector has been a limiting factor in probing LLP lifetimes less than 100mm. To circumvent the difficulty of triggering on LLP decays, the search presented in this thesis exploits the ZH associated production mode, relying on leptonic trigger signatures to select interesting events. This is the first search for Higgs boson decays into LLPs to exploit this analysis methodology and additionally makes use of several novel methods for both background rejection and background estimation. No excess over Standard Model predictions is observed, and upper limits are set on the branching ratio of the Higgs boson to LLPs . Depending on the mass of the LLP, branching ratios greater than 10% are excluded for lifetimes as small as 4mm and as large as 100mm, probing an important gap in the ATLAS exotic Higgs decay programme. In comparison to the previous searches for Higgs decays to LLPs, these are among the most stringent limits placed on this scenario, and for LLPs with masses below 40 GeV these results represent the strongest existing constraints on the branching ratio of the Higgs boson to LLPs in this lifetime regime.

Fundamental physics research aims to understand the theory of particle interactions, the Standard Model (SM) of particle physics being the current best theory of the electroweak and strong forces. Modern efforts seeks to explain phenomenon like the matter antimatter asymmetry of the universe and the nature of dark matter using various experimental modalities such as terrestrial particle colliders like the Large Hadron Collider (LHC). The ATLAS detector on the LHC is conducting a diverse physics program of precision SM measurements and searches for Physics beyond the SM using deeply inelastic scattering products to study fundamental physics. The original research presented here uses proton collision data from the ATLAS detector to search for an exotic decay mode of the Higgs boson coupling to a new light scalar field. Additionally, two research projects are presented to improve the performance of the ATLAS detector. The first introduces a novel algorithm to improve the efficiency of locating interesting physics within saved events. The second improves the jet calibration procedure by enabling the use of gradient based regression with a novel objective function along with a unified neural network based framework. Additionally, a network of quantum sensors are in development to enhance the physics reach of modern detectors and expand the set of models of new physics that can be experimentally probed. One such technology is atomic gradiometer interferometric sensors, like the MAGIS-100 experiment, that utilize matter waves to search for ultralight bosonic dark matter. The research and development of a novel light field imaging device is presented here for the MAGIS-100 experiment, as part of a burgeoning collaboration between the high energy physics (HEP) and the atomic, molecular, and optical (AMO) physics communities.

This book explores the Higgs boson and its interactions with fermions, as well as the detector technologies used to measure it. The Standard Model of Particle Physics has been a groundbreaking theory in our understanding of the fundamental properties of the universe, but it is incomplete, and there are significant hints which require new physics. The discovery of the Higgs boson in 2012 was a substantial confirmation of the Standard Model, but many of its decay modes remain elusive. This book presents the latest search for Higgs boson decays into c-quarks using a proton-proton collision dataset collected by the ATLAS experiment at the Large Hadron Collider (LHC). This decay mode has yet to be observed and requires advanced machine learning algorithms to identify c-quarks in the experiment. The results provide an upper limit on the rate of Higgs boson decays to c-quarks and a direct measurement of the Higgs boson coupling strength to c-quarks. The book also discusses the future of particle physics and the need for significant improvements to the detector to cope with increased radiation damage and higher data rates at the High-Luminosity LHC. It presents the characterization of the ATLAS pixel detector readout chip for the inner detector upgrade (ITk). The chip was subjected to irradiations using X-rays and protons to simulate the radiation environment at the HL-LHC. The tests showed that all readout chip components, including the digital logic and analogue front-end, are sufficiently radiation-tolerant to withstand the expected radiation dose. Finally, this book describes monolithic pixel detectors as a possible technology for future pixel detectors. This book is ideal for individuals interested in exploring particle physics, the Higgs boson, and the development of silicon pixel detectors.

This Thesis describes the first measurement of, and constraints on, Higgs boson production in the vector boson fusion mode, where the Higgs decays to b quarks (the most common decay channel), at the LHC. The vector boson fusion mode, in which the Higgs is produced simultaneously with a pair of quark jets, provides an unparalleled opportunity to study the detailed properties of the Higgs, including the possibility of parity and CP violation, as well as its couplings and mass. It thus opens up this new field of study for precision investigation as the LHC increases in energy and intensity, leading the way to this new and exciting arena of precision Higgs research.

During Run 2 of the Large Hadron Collider, the ATLAS experiment recorded proton-proton collision events at 13 TeV, the highest energy ever achieved in a collider. Analysis of this dataset has provided new opportunities for precision measurements of the Higgs boson, including its interaction with the top quark. The Higgs-top coupling can be directly probed through the production of a Higgs boson in association with a top-antitop quark pair (ttH). The Higgs to diphoton decay channel is among the most sensitive for ttH measurements due to the excellent diphoton mass resolution of the ATLAS detector and the clean signature of this decay. Event selection criteria were developed using novel Machine Learning techniques to target ttH events, yielding a precise measurement of the ttH cross section in the diphoton channel and a 6.3 $\sigma$ observation of the ttH process in combination with other decay channels, as well as stringent limits on CP violation in the Higgs-top coupling.