Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.

Recoge: 1. Introduction -- 2. Organisation -- Guiding principles for organising a colorectal cancer screening programme -- 3. Evaluation and interpretation of screening outcomes -- 4. Faecal occult blood testing -- 5. Quality assurance in endoscopy in colorectal cancer screening and diagnosis -- 6. Professional requirements and training -- 7. Quality assurance in pathology in colorectal cancer screening and diagnosis -- 8. Management of lesions detected in colorectal cancer screening -- 9. Colonoscopic surveillance following adenoma removal --10. Communication -- Appendices.

Dr. Soetikno has organized a comprehensive issue devoted to the detection and diagnosis of non-polypoid colorectal neoplasms with special emphasis on sessile or flat colon adenoma. Top experts in the field have supplied the latest clinical information in the following areas: Non-Polypoid Colorectal Neoplasms in Ulcerative Colitis; Detection and Diagnosis of Non-Polypoid Colorectal Neoplasms; Image-Enhanced Endoscopy to Detect and Diagnose Non-Polypoid Colorectal Neoplasms; CT Colonography and Non-Polypoid Colorectal Neoplasms, as well as Endoscopic Mucosal Resection of Non-Polypoid Colorectal Neoplasms. This issue is an important one as there are not many references on the topics that are as comprehensive.

Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.

This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.

Biomarkers and colorectal cancer.

A Working Group of 23 independent experts from 15 countries, convened by the International Agency for Research on Cancer (IARC) in November 2017, reviewed the scientific evidence and assessed the cancer-preventive and adverse effects of various methods of screening for colorectal cancer. Colorectal cancer is the third most common cancer in men and the second most common in women worldwide, and represents more than 10% of the global cancer burden. This publication provides evidence-based evaluations of the effectiveness of colorectal cancer screening in reducing colorectal cancer incidence and mortality. The Working Group also reviewed the body of evidence on the comparison of endoscopic and stool-based techniques, on the determinants of participation in screening programs, and on the most mature emerging techniques that may be alternatives to current practices for colorectal cancer screening, as well as presenting the different categories of high-risk populations and the surveillance strategies for such individuals.