Robust Methods for Data Reduction gives a non-technical overview of robust data reduction techniques, encouraging the use of these important and useful methods in practical applications. The main areas covered include principal components analysis, sparse principal component analysis, canonical correlation analysis, factor analysis, clustering, dou

Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

A textbook covering data-science and machine learning methods for modelling and control in engineering and science, with Python and MATLAB®.

The last few years have seen a great increase in the amount of data available to scientists, yet many of the techniques used to analyse this data cannot cope with such large datasets. Therefore, strategies need to be employed as a pre-processing step to reduce the number of objects or measurements whilst retaining important information. Spectral dimensionality reduction is one such tool for the data processing pipeline. Numerous algorithms and improvements have been proposed for the purpose of performing spectral dimensionality reduction, yet there is still no gold standard technique. This book provides a survey and reference aimed at advanced undergraduate and postgraduate students as well as researchers, scientists, and engineers in a wide range of disciplines. Dimensionality reduction has proven useful in a wide range of problem domains and so this book will be applicable to anyone with a solid grounding in statistics and computer science seeking to apply spectral dimensionality to their work.

The uncertainty that researchers face in specifying their estimation model threatens the validity of their inferences. In regression analyses of observational data, the 'true model' remains unknown, and researchers face a choice between plausible alternative specifications. Robustness testing allows researchers to explore the stability of their main estimates to plausible variations in model specifications. This highly accessible book presents the logic of robustness testing, provides an operational definition of robustness that can be applied in all quantitative research, and introduces readers to diverse types of robustness tests. Focusing on each dimension of model uncertainty in separate chapters, the authors provide a systematic overview of existing tests and develop many new ones. Whether it be uncertainty about the population or sample, measurement, the set of explanatory variables and their functional form, causal or temporal heterogeneity, or effect dynamics or spatial dependence, this book provides guidance and offers tests that researchers from across the social sciences can employ in their own research.

This highly accessible book presents robustness testing as the methodology for conducting quantitative analyses in the presence of model uncertainty.