Advances in Radiation Biology: Relative Radiation Sensitivities of Human Organ Systems, Part III, is the third volume of the series "Relative Radiation Sensitivities of Human Organ Systems." It presents reviews of organ systems not included in the preceding two parts (Advances in Radiation Biology, Volumes 12 and 14). The subject matter contained in the current volume is viewed through the eyes of the radiation therapist. Although the presentations have strong clinical overtones, an effort has been made, wherever possible, also to address the radiobiological bases of radiation sensitivity of organs. The book contains seven chapters and begins with a study on radiation damage to the kidney. This is followed by separate chapters on inherent or intrinsic radiosensitivity of human cells; the impact of brachytherapy (i.e., short-distance radiation treatment using photon radiation) on tumors; and human tissue tolerance to fast neutron radiotherapy. Subsequent chapters deal with normal tissue effects of combined hyperthermia and radiotherapy; the impact of ionizing radiation on the successive stages of human development in utero; and developments in theoretical knowledge and practical applications of ionizing radiations which have taken place in a little less than a century.

Advances in Radiation Biology, Volume 12: Relative Radiation Sensitivities of Human Organ Systems covers articles on the response of selected human organ and tissue systems to exposure to ionizing radiation. The book presents articles on the relative radiosensitivities of the thymus, spleen, lymphohemopoietic systems, small and large intestines, oral cavity, larynx, pharynx, and esophagus. The text also includes articles on the relative radiation sensitivity of the integumentary system, as well as the relative radiosensitivity of the human lung and fetal tissues. The tolerance of the central and peripheral nervous system to therapeutic irradiation is also encompassed. Radiation biologists, oncologists, physicians, pediatricians, and medical students will find the book useful.

Advances in Radiation Biology, Volume 14: Relative Radiation Sensitivities of Human Organ Systems, Part II focuses on radiation sensitivities of particular human organ systems. The sensitivities are then assessed based on the severity and the rapidity in which the effects of radiation manifest. The opening chapter surveys the clinical and experimental data on approaches toward the prevention of bladder complications in clinical radiotherapy. A discussion on HeLa cells, which are of special importance in human cervical cancer therapy, is then presented. In presenting this topic, this book emph ...

Advances in Radiation Biology, Volume18: Relative Radiation Sensitivities of Human Organ Systems, Part IV focuses on the sensitivity of certain human organ systems to radiation exposure. This book discusses the radiation sensitivity of the prostate and radiation therapy of its tumors; clinical radiobiology and normal-tissue morbidity after breast cancer treatment; and approach to optimal therapy and normal-tissue sparing. The fractionation sensitivity of mammalian tissues; trends for improving radiation sensitivity by counteracting chronic and acute hypoxia; and predictive assays in radiation therapy are also elaborated. This publication likewise covers the basic cellular radiobiology and its significance for radiation therapy and classical theoretical approaches to cellular radiosensitivity. This volume is beneficial to clinicians and students intending to gain knowledge of the radiation sensitivities of human organ systems.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.