This issue of Physical Medicine and Rehabilitation Clinics of North America will cover regenerative medicine. Rapid advances in stem cell science are opening new avenues for drug discovery and may lead to new uses of stem cells for other musculoskeletal disorders. Artcles to be included are: Evidence-Based Regenerative Prolotherapy and Perineural Injection Approaches; Platelet Rich Plasma; Autologous Conditioned Serum; Stem Cell Considerations for the Clinician; Adipose Derived Stromal Vascular Faction and Stem Cell Use, as well as many others.

Guest edited by Drs. Joel Stein and Leroy R. Lindsay, this issue of Physical Medicine and Rehabilitation Clinics will cover several key areas of interest related to Technological Advances in Rehabilitation. This issue is one of four selected each year by our series Consulting Editor, Dr. Santos Martinez of the Campbell Clinic. Articles in this issue include, but are not limited to: Functional Electrical Stimulation; Non-Invasive Brain Stimulation; Spinal Cord Stimulation for Motor Rehabilitation; Robotics for Limb Rehabilitation; Virtual Reality and Gaming; New Technologies in Prosthetics and Amputee Rehabilitation; Regenerative Medicine; Smart Homes and other Technology for Adaptive Living; Big Data and Rehabilitation; and Telemedicine in Rehabilitation.

In this issue of Physical Medicine and Rehabilitation Clinics, guest editors Drs. Michael Khadavi and Luga Podesta bring their considerable expertise to the topic of Orthobiologics. Use and research surrounding naturally derived substances that are used to help heal and repair orthopedic injuries are expanding rapidly. In this issue, top experts discuss the most up-to-date uses of orthobiologics in the rehabilitation setting. Contains 16 practice-oriented topics including orthobiologics for spine disorders; evidence and techniques in prolotherapy; orthobiologic interventions for muscle injuries; special populations in orthobiologics: athletic, elderly, and pediatrics populations; rehabilitation protocols for orthobiologic procedures; orthobiologic techniques for surgical augmentation; and more. Provides in-depth clinical reviews on orthobiologics, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue is a comprehensive, multi-disciplinary state-of-the-art review focusing on the athlete as a whole. The articles explore the impact of excessive activity, new therapies and performance enhancement interventions on the musculoskeletal, neurological and psychological aspects of the athlete.

This contributed volume presents the current state of research on regenerative rehabilitation across a broad range of neuro- and musculoskeletal tissues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue types and their inherent plasticity. The latter quality is what enables these tissues to adapt to mechanical and/or chemical cues to improve functional capacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function. Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field.

CDC estimates reveal that 1.6 million to 3.8 million concussions occur each year. This issue will include topics such as pathophysiology, imagine, rturn to learn programs and long-term consequences of concussions.