Pyrrhic Progress analyses over half a century of antibiotic use, regulation, and resistance in US and British food production. Mass-introduced after 1945, antibiotics helped revolutionize post-war agriculture. Food producers used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals' growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics. Pyrrhic Progress reconstructs the complicated negotiations that accompanied this process of risk prioritization between consumers, farmers, and regulators on both sides of the Atlantic. Unsurprisingly, solutions differed: while Europeans implemented precautionary antibiotic restrictions to curb AMR, consumer concerns and cost-benefit assessments made US regulators focus on curbing drug residues in food. The result was a growing divergence of antibiotic stewardship and a rise of AMR. Kirchhelle's comprehensive analysis of evolving non-human antibiotic use and the historical complexities of antibiotic stewardship provides important insights for current debates on the global burden of AMR.

Winner of the 2021 Joan Thirsk Memorial Prize from the British Agricultural History Society​ 2020 Choice​ Outstanding Academic Title​ Winner of the 2020 Turriano Prize from ICOHTEC Short-listed and highly commended for the Antibiotic Guardian Award from Public Health England​ Long-listed for the Michel Déon Prize from the Royal Irish Academy​ Pyrrhic Progress analyses over half a century of antibiotic use, regulation, and resistance in US and British food production. Mass-introduced after 1945, antibiotics helped revolutionize post-war agriculture. Food producers used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics. Pyrrhic Progress reconstructs the complicated negotiations that accompanied this process of risk prioritization between consumers, farmers, and regulators on both sides of the Atlantic. Unsurprisingly, solutions differed: while Europeans implemented precautionary antibiotic restrictions to curb AMR, consumer concerns and cost-benefit assessments made US regulators focus on curbing drug residues in food. The result was a growing divergence of antibiotic stewardship and a rise of AMR. Kirchhelle’s comprehensive analysis of evolving non-human antibiotic use and the historical complexities of antibiotic stewardship provides important insights for current debates on the global burden of AMR. This Open Access ebook is available under a CC-BY-NC-ND license, and is supported by a generous grant from Wellcome Trust.

The lives of four high school seniors intersect weeks before a meteor is set to pass through Earth's orbit, with a 66.6% chance of striking and destroying all life on the planet.

Eighteenth-century natural historians created a peculiar, and peculiarly durable, vision of nature--one that embodied the sexual and racial tensions of that era. When plants were found to reproduce sexually, eighteenth-century botanists ascribed to them passionate relations, polyandrous marriages, and suicidal incest, and accounts of steamy plant sex began to infiltrate the botanical literature of the day. Naturalists also turned their attention to the great apes just becoming known to eighteenth-century Europeans, clothing the females in silk vestments and training them to sip tea with the modest demeanor of English matrons, while imagining the males of the species fully capable of ravishing women.

In the early 1990s, Russian President Boris Yeltsin revealed that for the previous thirty years the Soviet Union had dumped vast amounts of dangerous radioactive waste into rivers and seas in blatant violation of international agreements. The disclosure caused outrage throughout the Western world, particularly since officials from the Soviet Union had denounced environmental pollution by the United States and Britain throughout the cold war. Poison in the Well provides a balanced look at the policy decisions, scientific conflicts, public relations strategies, and the myriad mishaps and subsequent cover-ups that were born out of the dilemma of where to house deadly nuclear materials. Why did scientists and politicians choose the sea for waste disposal? How did negotiations about the uses of the sea change the way scientists, government officials, and ultimately the lay public envisioned the oceans? Jacob Darwin Hamblin traces the development of the issue in Western countries from the end of World War II to the blossoming of the environmental movement in the early 1970s. This is an important book for students and scholars in the history of science who want to explore a striking case study of the conflicts that so often occur at the intersection of science, politics, and international diplomacy.

With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.