Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful and theoretically complex analytical tool. Basic 1H- and 13C-NMR Spectroscopy provides an introduction to the principles and applications of NMR spectroscopy. Whilst looking at the problems students encounter when using NMR spectroscopy, the author avoids the complicated mathematics that are applied within the field. Providing a rational description of the NMR phenomenon, this book is easy to read and is suitable for the undergraduate and graduate student in chemistry. - Describes the fundamental principles of the pulse NMR experiment and 2D NMR spectra - Easy to read and written with the undergraduate and graduate chemistry student in mind - Provides a rational description of NMR spectroscopy without complicated mathematics

Carbon-13 NMR Spectroscopy focuses on the potential of 13C techniques and the practical difficulties associated with the detection of 13C NMR absorption. This monograph includes a descriptive presentation of 13C shielding results that has been adopted with emphasis on the structural and stereochemical aspects. Organized into four parts encompassing 11 chapters, this book starts with an overview of the characteristics of the NMR signals derived from compounds containing 13C nuclei in natural abundance that are inherently much weaker than those exhibited by protons. This monograph then compares the primary characteristics of 13C NMR with the more familiar proton methods. Other chapters consider the 13C spectra of pyridine, pyridazine, pyrimidine, pyrazine, s-triazine, and s-tetrazine. The final chapter deals with the effects of solute–solvent interactions on the shieldings of other nuclei. This monograph is intended for organic chemists, graduate students, and researchers in various branches of chemistry with an interest in 13C NMR methods as another approach to chemical problems.

With the advent of Fourier transform spectrometers of great sensitivity, it has become practical to obtain carbon-13 nuclear magnetic resonance (C-13 NMR; l3C NMR; CMR) spectra routinely on organic molecules, and this technique has become one of the highest utility in determining structures of organic unknowns. When the usual spectrometric techniques proton magnetic resonance (H-I NMR; IH NMR; PMR), infrared (lR), mass (MS), and ultraviolet (UV)-do not readily reveal a compound's structure, a C-13 NMR spectrum will often provide sufficient additional information to yield it unequivocally. With this in mind, the present work was designed to give advanced undergraduates, graduate students, and practicing chemists a working knowledge of and facility with the use of this valuable technique. Some familiarity with other spectrometric techniques is assumed (recommended book: Silverstein, Bassler, and Morrill, Spectrometric Identification of Organic Compounds), but no prior knowledge of C-13 NMR -which is treated very lightly, if at all, in the widely used elementary organic texts-is necessary. A discussion of C-13 NMR spectroscopy is followed by 125 problems, each consisting of a molecular formula, two types of C-13 NMR spectra (partially and completely proton decoupled, with connecting lines to facilitate multiplicity assignments), an integrated H-I NMR spectrum, and the most important IR, UV, and MS data. These problems have been very carefully prepared, thoroughly tested by students at the University of Arizona, and we believe that very few errors remain.

Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Represents the largest collection of polymer NMR spectra availableThis unique source of information provides a fingerprint of individual polymers, so the microstructure or fine structure of the polymer can be readily identified. Appropriate NMR analysis conditions (solvent(s), temperature, pulse angle, etc.) are specified for each polymer sample. All the resonances, often obtained at different frequencies, are interpreted with remarks concerning the homopolymer or copolymer skeletons. Contains over 530 1H and 13C NMR spectra of soluble and swollen gelled 13C polymers Includes new NMR polymer spectra, together with those previously published Comprehensive bibliography Spectra are grouped into families for ready-searching CD-ROM is fully searchable and user-friendly 5th Edition of popular reference work An essential reference for polymer chemists and physicists in research and industrial analytical laboratories.

An understanding of spectroscopic techniques in the analysis of chemical structures is essential to all chemistry degree courses. This new addition to the Oxford Chemistry Primers series provides the essential material needed by undergraduates, in a compact form. It will be beneficial to postgraduates in organic chemistry as reference material in their daily research.

For almost a quarter of a century the words "nuclear magnetic reso nance" were synonymous with proton I,leasurements. During this period the literature abounded with a seemingly infinite variety of 1H NHR studies concerned primarily with carbon chemistry. Occasionally a "novel" nucleus was studied and, even in those early days, the poten- 13 14 31 19 tial offered by C, N, P and F was clearly recognized. Despite the allure, the technical difficulties involved in measuring some of these nuclei were far from trivial. Small magnetic moments and low natural abundance in combination with spin-spin coupling from other nuclei, mostly protons, resulted in a signal-to-noise problem whose severity effectively excluded the study of metal complexes with unfa vorable solubility characteristics. The first important breakthrough came with the advent of broad band 1H-decoupling. For example, the featureless broad 31p resonance associated with the commonly used ligand triphenyl phosphine is converted to a sharp, more readily ob served singlet when wide-band decoupling is employed (see Fig. 1). Despite this improvement investigation of more interesting molecules, such as catalytically active complexes was forced to await the devel opment of Fourier Transform methods since only with relatively rapid signal averaging methods could sufficient signal-to-noise ratios be achieved.