Protein-Protein and Domain-Domain Interactions
Title | Protein-Protein and Domain-Domain Interactions PDF eBook |
Author | Pandjassarame Kangueane |
Publisher | Springer |
Pages | 216 |
Release | 2018-02-16 |
Genre | Medical |
ISBN | 9811073473 |
This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions. The significance of such complex formation in human biology in the light of molecular evolution is also highlighted using several examples. The chapters also describe recent advancements on the molecular principles of protein-protein interaction with reference to evolution towards target identification in drug discovery. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with the molecular interaction of proteins.
Protein-protein Interactions and Networks
Title | Protein-protein Interactions and Networks PDF eBook |
Author | Anna Panchenko |
Publisher | Springer Science & Business Media |
Pages | 198 |
Release | 2010-04-06 |
Genre | Science |
ISBN | 1848001258 |
The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks.
Modular Protein Domains
Title | Modular Protein Domains PDF eBook |
Author | Giovanni Cesareni |
Publisher | John Wiley & Sons |
Pages | 524 |
Release | 2006-03-06 |
Genre | Science |
ISBN | 3527605894 |
Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique reference source covers all relevant protein domains, including SH2, SH3, PDZ, WW, PTB, EH, PH and PX. Its user-oriented concept combines broad coverage with easy retrieval of essential information, and includes a special section on Web-based tools and databases covering protein modules and functional peptide motifs. Essential for the study of protein-protein interactions in vivo or in silico, and a prerequisite for successful functional proteomics studies. With a prologue by Sir Tom Blundell.
Biotechnology
Title | Biotechnology PDF eBook |
Author | Mehdi Khosrowpour |
Publisher | Medical Information Science Reference |
Pages | 0 |
Release | 2019 |
Genre | Bioengineering |
ISBN | 9781522589037 |
Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.
Proteomics and Protein-Protein Interactions
Title | Proteomics and Protein-Protein Interactions PDF eBook |
Author | Gabriel Waksman |
Publisher | Springer Science & Business Media |
Pages | 325 |
Release | 2006-12-22 |
Genre | Medical |
ISBN | 0387245324 |
Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London WC1E 7H United Kingdom Email: g. waksman@bbk. ac. uk and g. waksman@ucl. ac. uk Phone: (+44) (0) 207 631 6833 Fax: (+44) (0) 207 631 6833 URL: http://people. cryst. bbk. ac. uk/?ubcg54a Gabriel Waksman is Professor of Structural Molecular Biology at the Institute of Structural Molecular Biology at UCL/Birkbeck, of which he is also the director. Before joining the faculty of UCL and Birkbeck, he was the Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics at the Washington University School of Medicine in St Louis (USA). The rapidly evolving ?eld of protein science has now come to realize the ubiquity and importance of protein–protein interactions. It had been known for some time that proteins may interact with each other to form functional complexes, but it was thought to be the property of only a handful of key proteins. However, with the advent of hi- throughput proteomics to monitor protein–protein interactions at an organism level, we can now safely state that protein–protein interactions are the norm and not the exception.
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
Title | TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF eBook |
Author | Wolfgang B. Liedtke, MD, PH.D. |
Publisher | CRC Press |
Pages | 502 |
Release | 2006-09-29 |
Genre | Medical |
ISBN | 1420005847 |
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Protein-protein Interactions
Title | Protein-protein Interactions PDF eBook |
Author | Erica A. Golemis |
Publisher | CSHL Press |
Pages | 954 |
Release | 2005 |
Genre | Interactions protéine-protéine - Manuels de laboratoire |
ISBN | 0879697237 |
Reflecting the various advances in the field, this book provides comprehensive coverage of protein-protein interactions. It presents a collection of the technical and theoretical issues involved in the study of protein associations, including biophysical approaches. It also offers a collection of computational methods for analyzing interactions.