Rheumatoid Arthritis - Other Perspectives towards Better Practice sheds light on the disease process of rheumatoid arthritis as well as the disease’s related comorbidities. Chapters cover such topics as immune-pathogenic theories, classification criteria, available composite measures of disease assessment, and latest available therapeutic approaches.

Issues in Rheumatology Research and Practice: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Rheumatology Research and Practice. The editors have built Issues in Rheumatology Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Rheumatology Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Rheumatology Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Arthritis Research: Methods and Protocols, Second Edition expands upon the first edition to present new and current techniques for the research of arthritis and related conditions. A compendium of leaders in the field contribute chapters that cover practical research methods such as the intravital multiphoton microscopy technique, techniques for evaluating exhausted CD8 T cell and for studying nucleic acid sensors and their effects, methods for in vivo tetracycline-controlled transgenic mice and T cell receptor transgenic mice, protocols to detect V(D)J recombination products and microRNA, and the technique to make bleomycin-induced dermal fibrosis. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Arthritis Research: Methods and Protocols, Second Edition will serve both professionals and novices with state-of-the-art techniques pertaining to this fascinating research field.

This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rheumatoid Arthritis: Methods and Protocols aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study.

There has been a revolution in treatments for inflammatory arthritis. Mostly, this is due to the introduction of biologics, particularly TNF inhibitors. These have changed approach to treatment in two ways. First, they appear substantially more effective than conventional drugs. Second, they are far more expensive than traditional treatment approaches. One consequence of this therapeutic revolution is a need to better understand arthritis and to place the new biological treatments into the context of existing management approaches.

Bringing together the expertise of an international group of contributors, the editors set out to address the most contentious issues posed by the problem of rheumatoid arthritis. The result is a series of state-of-the-art review papers on the subject that will interest all rheumatologists wishing to keep abreast of this fast-moving field.