CD-ROM includes all of files necessary to complete the tutorials in the book.

MacLife is the ultimate magazine about all things Apple. It’s authoritative, ahead of the curve and endlessly entertaining. MacLife provides unique content that helps readers use their Macs, iPhones, iPods, and their related hardware and software in every facet of their personal and professional lives.

Master the role and responsibilities of the PN in Canadian medical-surgical nursing! The only Canadian medical-surgical nursing text designed for the Practical Nurse student, Linton and Matteson's Medical-Surgical Practical Nursing in Canada provides a solid foundation in the fundamentals of nursing, including roles, settings, and issues and trends in health care. Content includes descriptions of pathology, medical conditions organized by body system, emergency and disaster management, pandemic preparedness, and mental health nursing. Unique to this text is a unit focusing on the older adult — a key patient population that PNs see in practice. Edited by Katherine Poser, an experienced educator and critical care nurse, this text helps you prepare for the REx-PN® or CPNRE® licensure examinations and succeed as a new nurse.

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery. Fragment-Based Drug Discovery: A Practical Approach is a guide to the techniques and practice of using fragments in drug screening. The emphasis is on practical guidance, with procedures, case studies, practical tips, and contributions from industry. Topics covered include: an introduction to fragment based drug discovery, why using fragments is a more efficient process than predominant models, and what it means to have a successful FBDD effort. setting up an FBDD project library building and production NMR in fragment screening and follow up application of protein-ligand NOE matching to the rapid evaluation of fragment binding poses target immobilized NMR screening: validation and extension to membrane proteins in situ fragment-based medicinal chemistry: screening by mass spectrometry computational approaches to fragment and substructure discovery and evaluation virtual fragment scanning: current trends, applications and web based tools fragment-based lead discovery using covalent capture methods case study from industry: the identification of high affinity beta-secretase inhibitors using fragment-based lead generation With contributions from industry experts who have successfully set up an industrial fragment-based research program, Fragment-Based Drug Discovery: A Practical Approach offers essential advice to anyone embarking on drug discovery using fragments and those looking for a new approach to screening for drugs.

This guide is all beginner and intermediate speakers need to go beyond bonjour and au revoir. This oversized workbook has more than 200 written and audio exercises for a complete learning experience. This book is the ultimate resource for you to improve your French. In no time, you'll be speaking like a true Parisien!