Contributors were asked to emphasize their own experience with nanoparticles or microspheres. They were also encouraged to provide aspects normally not stipulated in specialized reviews. The objective was to produce a book which although written by specialists, presented a subject which could be easily understood by people in different fields of life sciences. Another goal was to set up a condensed work covering many aspects of nanoparticles and microspheres. That is the reason why, although mainly dealing with synthetic drug carriers, the first chapter is related to preparation and physicochemical properties of nanoparticles constructed from natural polymers. This is followed by two chapters involving the application of polymeric drug carriers in cancer therapy. The second chapter extensively describes in vitro and in vivo behaviour of purely synthetic nanoparticles. As ub the case of liposomes, a problem can be that some particles are preferentially taken up by the reticuloendothelial system. Magnetic drug carriers provide a partial answer to this problem since their tropism can be managed by an external magnet. The third chapter is entirely devoted to this aspect. A brief but original application of nanoparticles is given in the fourth chapter by reviewing their use in ocular therapy. Finally, two general applications of polymeric microspheres are discussed in chapters 5 and 6.

The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

Contributors were asked to emphasize their own experience with nanoparticles or microspheres. They were also encouraged to provide aspects normally not stipulated in specialized reviews. The objective was to produce a book which although written by specialists, presented a subject which could be easily understood by people in different fields of life sciences. Another goal was to set up a condensed work covering many aspects of nanoparticles and microspheres. That is the reason why, although mainly dealing with synthetic drug carriers, the first chapter is related to preparation and physicochemical properties of nanoparticles constructed from natural polymers. This is followed by two chapters involving the application of polymeric drug carriers in cancer therapy. The second chapter extensively describes in vitro and in vivo behaviour of purely synthetic nanoparticles. As ub the case of liposomes, a problem can be that some particles are preferentially taken up by the reticuloendothelial system. Magnetic drug carriers provide a partial answer to this problem since their tropism can be managed by an external magnet. The third chapter is entirely devoted to this aspect. A brief but original application of nanoparticles is given in the fourth chapter by reviewing their use in ocular therapy. Finally, two general applications of polymeric microspheres are discussed in chapters 5 and 6.

The continued advancement in the sciences of functional foods and nutraceuticals has clearly established a strong correlation between consumption of bioactives and improved human health and performance. However, the efficacy and bioavailability of these bioactive ingredients (e.g., omega-3 oils, carotenoid antioxidants, vitamins, and probiotic bacteria) in foods often remains a challenge, due to their instability in food products and gastrointestinal tract, as well as their limited bioavailability. In some cases, these bioactive ingredients may impart an undesirable organoleptic characteristic to the final product, which hinders acceptance by consumers. In addressing these challenges, development of effective delivery systems is critical to meet the consumer needs for effective bioactives. The scientific knowledge behind developing effective delivery of bioactive components into modern and wide-ranging food products will be essential to reap their health-promoting benefits and to support the sustained growth of the functional foods market. Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients explores the current data on all aspects of nanoscale packing, carrying and delivery mechanisms of bioactives ingredients to functional foods. The book presents various delivery systems (including nano-emulsions, solid lipid nanoparticles, and polymeric nano-particles), their properties and interactions with other food components, and fate in the human body. Later chapters emphasize the importance of consumers attitude towards nano-delivery for the success of the technology and investigate the challenges faced by regulatory agencies to control risks and harmonize approaches worldwide. The wide applicability of bioactive delivery systems with the purpose of improving food quality, food safety and human health will make this book a worthy reference for a diverse range of readers in industry, research and academia.

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.