Presents seven papers from an October 1998 symposium, of interest to those responsible for translating bench chemistry up to 10-100 liter pilot plants and for those responsible for operating such pilot plants. Looks at productivity, particularly in relation to batch processing and meeting the threat from overseas manufacturing, and details a collaboration project between industry and academia in the UK. Discusses chemical aspects of scale-up, the use of phase transfer catalysis, control of crystallization, and scale-up of organo-lithium and Grignard reactions. Safety concepts are also covered. Annotation copyrighted by Book News, Inc., Portland, OR

One of the biggest challenges facing today's chemist and chemical engineer is the translation of bench chemistry to the pilot plant. This book provides expert insights into current best practice, and will prove an indispensable manual for all those involved in pilot plant design and scale-up implementation - process chemists, engineers and managers alike. The international expertise of the contributors covers a wide range of topics, and new material covered includes: the removal of heavy metals from effluent, heat flow calorimetry, low temperature processes, good manufacturing practice in pilot plants, design issues, the use of statistical methods in the running of pilot plants. Pilot Plants and Scale-Up of Chemical Processes is a must for all those who are, and wish to remain, expert in the field, providing for the first time in print, a comprehensive and unique perspective of pilot plant production.

Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.

Chemical Projects Scale Up: How to Go from Laboratory to Commercial covers the chemical engineering steps necessary for taking a laboratory development into the commercial world. The book includes the problems associated with scale up, equipment sizing considerations, thermal characteristics associated with scale up, safety areas to consider, recycling considerations, operability reviews and economic viability. In addition to the process design aspects of commercializing the laboratory development, consideration is given to the utilization of a development in an existing plant. - Explains how heat removal for exothermic reactions can be scaled up - Outlines how a reactor can be sized from batch kinetic data - Discusses how the plant performance of a new catalyst can be evaluated - Presents how the economics of a new product/process can be developed - Discusses the necessary evaluation of recycling in commercial plants

Handbook for chemists, chemical engineers, technicians. Information on chemicals, solvents, gases, materials, the selection of reactors, chillers, filters, pumps and other equipment, conversion factors, mathematical formulas, fundamentals of heat transfer, temperature control, safe operation of electrical equipment, chemical hygiene & safety, plus rules of thumb and recommendations for the safe, efficient operation of a small chemical pilot facility.