Photochemistry and Photobiology of Nucleic Acids: Volume II, Biology is a collection of papers that deals with the biological effects due to stable UV induced alterations in critical cellular macromolecules, including cell death, growth delay, mutagenesis, and carcinogenesis. The papers assume that DNA is the macromolecule most relevant to cell pathology, as well as to the photochemical and photobiological properties of RNA which are essential in cellular functions. One paper investigates the UV-induced cross-linkings of proteins with nucleic acids as a possible cause of biological effects other than just in terms of the damage done to nucleic acids. Other papers discuss the mechanisms of protection against, and in the repair of damage caused by UV photons and by ionizing radiation (also chemical mutagens) in many organisms from viruses to mammalian cells. The repair processes appear to play a role in monitoring and preserving the structural integrity of DNA during physiological processes such as replication and transcription. One paper notes that in experiments on human embryonic lung fibroblasts WI-38 at very high radiation doses, radiation products of Thy in acid-soluble form appear while products from the DNA (acid-precipitable fraction) disappear. The paper suggests that the excision process is therefore selective. The collection is suitable for biochemists, microbiologists, or academicians whose works involve genetics, cancer, and cellular research.

Although there are several excellent books covering a few of the specialized areas of photobiology, at the present time there is no book that covers all areas of the science of photobiology. This book attempts to fill this void. The science of photobiology is currently divided into 14 subspecialty areas by the American Society for Photobiology. The first 14 chapters of this book deal with those subspecialty areas, each written by a leader in the field. Chapter 15, entitled "New Topics in Photobiology," highlights areas of research that may be desig nated sUbspecialties of photobiology in the future. This book has been written as a textbook to introduce the science of photobiology to advanced undergraduate and graduate students. The chapters are written to provide a broad overview of each topic. They are designed to contain the amount of information that might be presented in a one-to two-hour general lecture. The references are not meant to be exhaustive, but key refer ences are included to give students an entry into the literature. Frequently a more recent reference that reviews the literature will be cited rather than the first paper by the author making the original discovery. Whenever practical, a classroom demonstration or simple laboratory exercise has been provided to exemplify one or more major points in a chapter.

The book is devoted to the consideration of the different processes taking place in thin films and at surfaces. Since the most important physico-chemical phenomena in such media are accompanied by the rearrangement of an intra- and intermolecular coordinates and consequently a surrounding molecular ensemble, the theory of radiationless multi-vibrational transitions is used for its description. The second part of the book considers the numerous surface phenomena. And in the third part is described the preparation methods and characteristics of different types of thin films. Both experimental and theoretical descriptions are represented. Media rearrangement coupled with the reagent transformation largely determines the absolute value and temperature dependence of the rate constants and other characteristics of the considered processes. These effects are described at the atomic or molecular level based on the multi-phonon theory, starting from the first pioneering studies through to contemporary studies.A number of questions are included at the end of many chapters to further reinforce the material presented.· Unified approach to the description of numerous physico-chemical phenomena in different materials· Based on the pioneering research work of the authors· Explantion of a variety of experimental observations· Material is presented at two levels of complexity for specialists and non-specialists · Identifies existing and potential applications of the processes and phenomena · Includes questions at the end of some chapters to further reinforce the material discussed

More than a simple survey of the current literature, Advances in Photochemistry offers critical evaluations written by internationally recognized experts. These pioneering scientists offer unique and varied points of view of the existing data. Their articles are challenging as well as provocative and are intended to stimulate discussion, promote further research, and encourage new developments in the field. This series provides photochemists a forum for critical, authoritative evaluations of advances in every area of photochemistry, including organic, inorganic, and biological topics. Volume 26 continues to report recent advances with a significant, up-to-date selection of papers by internationally recognized researchers. Topics include: Photochemistry of triarylmethane dye leuconitrites. Structure and reactivity of organic intermediates as revealed by time-resolved infrared spectroscopy. Semiconductor photocatalysis for organic synthesis. Photophysical probes of DNA sequence-directed structure and dynamics

Our knowledge of the photodegradation of polymers, chemical evolution, photosynthesis, visual perception and the biological effects of light depends heavily on our ability to elucidate the primary photochemical processes of macromolecules. This volume brings together for the first time from the fields of natural as well as synthetic polymers a group of reports dealing with macromolecular photochemistry. Since macromolecular photo chemistry is an expanding new field that crosses the boundaries between classical disciplines, the reader will encounter the employment of diverse scientific approaches and unfamiliar terminology. However, it has become increasingly apparent that researchers in these fields have much to learn from each other. Although this book is not intended to give a detailed survey of the photochemistry of macromolecules. it does represent the editor's perspective on the relationship between theory, kinetic studies and the synthesis aspects of photochemistry. The ideas expressed by the contributors offer a valuable com posite of theoretical and experimental approaches for those who are concerned with problems which have photochemical relevance, and show that investigators from different fields share many concepts and perhaps some common problems. This novel array of present knowledge should provide a basis for organizing and understanding photochemical information from chemistry, physics, biology and medicine. While of particular value to the research worker, the book also should be of interest to the graduate student about to embark on a problem in macromolecular photo chemistry.

Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.