Cette quatrième édition de Pharmacognosie, phytochimie, plantes médicinales a été profondément revue, restructurée et augmentée de 150 pages. Elle s'est enrichie des connaissances accumulées en une décennie sur les plantes et leurs produits d'usage récent ou confirmé. Comme les précédentes, la présente édition est construite sur les filiations biosynthétiques et évoque les différentes classes de métabolites primaires et secondaires des végétaux. Elle actualise les données botaniques, chimiques, analytiques, pharmacologiques et cliniques des plantes utilisées à des fins thérapeutiques aussi bien que l'évolution de la réglementation. Intégrant les données de l'édition 2008 de la Pharmacopée européenne et de ses quatre premiers suppléments (07/2009), elle inclut les conclusions des travaux du Comité européen des médicaments à base de plante mis en place après 2004 au sein de l'Agence européenne du médicament. Pour permettre aux professionnels de santé et aux utilisateurs de plantes de bien utiliser les plantes en situation de soins, cette quatrième édition privilégie les données factuelles leur permettant d'évaluer, au cas par cas, la balance bénéfices-risques. C'est ainsi qu'une place majeure est désormais accordée à l'évaluation clinique, aux effets indésirables et aux conditions d'emploi des plantes médicinales. Sans négliger pour autant les substances chimiquement définies obtenues à partir de ces plantes, ni leurs homologues hémisynthétiques ou synthétiques. Prenant en compte l'importance d'une alimentation riche en végétaux dans le maintien d'un bon état de santé, cette nouvelle édition aborde en détail le possible rôle préventif des micronutriments apportés par cette alimentation : fibres, polyphénols, composés soufrés, phyto-oestrogènes, tocophérols, carotènes et autres. Les informations présentées et commentées s'appuient sur une abondante bibliographie : une sélection de 1600 références reflétant la production scientifique des années 2000-2009 propose au lecteur, étudiant ou professionnel, des pistes choisies d'approfondissement.

Le préparateur en pharmacie – Guide théorique et pratique, 2e édition, aborde avec clarté et simplicité les différents aspects du savoir polyvalent que l’on attend du préparateur, appelé à seconder les pharmaciens titulaires et adjoints dans maintes tâches de l’officine : dispensation, conseil et information du public, préparation et réalisation des PDA (préparations des doses à administrer), vigilance, accueil et vente, documentation, gestion des stocks, administration, hygiène, diététique et maintien à domicile… Le personnel de l’officine doit aujourd’hui exercer sa mission de conseil avec d’autant plus de clairvoyance que le public, exposé à un discours médiatique et publicitaire à forte consonance scientifique, dispose de produits cosmétiques et de thérapeutiques « alternatives » où le naturel et le végétal jouent un très grand rôle, mais où les risques de l’automédication imposent un effort de pharmacovigilance et de toxicovigilance accru. Cette nouvelle édition, entièrement réactualisée, constitue un guide de référence pour les futurs préparateurs en pharmacie en respectant le référentiel du brevet professionnel, ainsi qu’un outil indispensable à la formation continue des préparateurs en mettant à leur disposition une somme d’informations facilement accessibles. Elle est également fort utile aux étudiants en pharmacie, dont le cursus comprend de nombreux stages : d’initiation officinale, d’application des enseignements coordonnés et de pratique professionnelle.

This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. - Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications - Includes a discussion of synergistic effects of formulations and antagonistic drug interactions - Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion

The current volume focuses on novel sources of biofungicides, primarily providing complete knowledge of microbial and phytochemical fungicides, studying antifungal activity mechanisms as well as their role in disease management in plants, and fungicide bioremediation. The use of biofungicides as eco-friendly alternative to typical synthetic fungicides is projected to play a significant role in organic farming in the future. Key Features: Discovers novel sources of biofungicides Describes the role of biofungicides in the control of plant diseases Studies antifungal activity mechanisms Explores how to survey and select promising biofungicides

This concise text on biologically active substances of the food, pharmaceutical and agricultural industries presents data on natural compounds of vegetable and animal origin. Various nutrients in food, phytochemicals and zoochemicals are discussed, including their uses for prophylactic, metaphylactic and therapeutic purposes in personalized medicine. Along with these compounds, prebiotics isolated by biotechnological methods from plant tissues are reviewed, with the aim of obtaining compounds with an oligoglucide structure. Metabolism of nutrients and the biodegradation of xenobiotics are hot topics and access routes into the human body for the various biologically active substances are covered. Features: Biologically active substances and related chemistry, biochemistry and agrochemistry data are rigorously discussed Data regarding natural compounds of vegetable origin detected from plants present in the spontaneous flora and plants obtained in agricultural crops (medicinal plants, aromatic plants and more) are presented Discusses the natural compounds of animal origin detected in the organisms of some terrestrial and aquatic animals Covers prebiotics isolated by technological and biotechnological methods from plant tissues, with the aim of obtaining compounds with oligoglucide structure Broad audience including all those in biochemistry, the food and pharmaceutical industries and agricultural fields

A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure. Key Features: Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognosy research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential Covers an extensive range of chemical, botanical and pharmacological diversities Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.