This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life‑cycle approach to managing pharmaceuticals in the environment. A policy mix of source‑directed, use‑orientated and end‑of‑pipe measures, involving several policy sectors, can help to improve health and protect the environment.

This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life-cycle approach to managing pharmaceuticals in the environment. A policy mix of source-directed, use-orientated and end-of-pipe measures, involving several policy sectors, can help to improve health and protect the environment

This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis.

Pharmaceuticals, due to their pseudo-persistence and biological activity as well as their extensive use in human and veterinary medicine, are a class of environmental contaminants that is of emerging concern. In contrast to some conventional pollutants, they are continuously delivered at low levels, which might give rise to toxicity even without high persistence rates. These chemicals are designed to have a specific physiological mode of action and to resist frequently inactivation before exerting their intended therapeutic effect. These features, among others, result in the bioaccumulation of pharmaceuticals which are responsible for toxic effects in aquatic and terrestrial ecosystems. It is extremely important to know how to remove them from the environment and/or how to implement procedures or treatments resulting in their biological inactivation. Although great advances have been made in their detection in aquatic matrices, there remains limited analytical methodologies available for the trace analysis of target and non-target pharmaceuticals in matrices such as soils, sediments, or biota. There are still many gaps in the data on their fate and behavior in the environment as well as on their threats to ecological and human health. This book has included nine current research and three review articles in this field.

The detection of pharmaceutical residues remained elusive until instruments such as liquid chromatography and mass spectrometry became commonplace in environmental laboratories. The documentation of the occurrence of pharmaceutical residues and endocrine disrupting chemicals in water resources has raused questions about their long-term effects in the ecosystem and their potential effects on human health. Fate of Pharmaceuticals in the Environment and in Water Treatment Systems covers critical issues regarding the occurrence, persistence, treatment, and transformations of pharmaceuticals in the environment and in drinking water and wastewater treatment systems. Acompilation of the recent literature, the book reviews advances in instrumentation and sample preparation techniques and includes an example of how risk assessment is conducted to investigate the fate and effects of pharmaceutical contaminants. Several chapters explore the behavior of pharmaceuticals in soil and the potential side effects of antibiotics on plants after uptake. Experts in drinking water and wastewater treatment systems present new findings on the effectiveness of current treatment practices to reduce the concentrations of pharmaceuticals at the source, providing new insights on how to better mitigate future problems brought about by emerging environmental contaminants. Contributing authors from academia, government, and industry provide a well-balanced multi-disciplinary perspective on the issues, discussing topics ranging from field studies documenting the occurrence of pharmaceuticals in environmental compartments, to laboratory studies determining the degradation kinetics and formation of by-products during treatment. The text discusses the factors that affect the environmental fate of pharmaceuticals in soil and water, facilitate the development of best management practices, and optimize treatment systems for removal of these compounds from the environment.

Microplastics are ubiquitous in the natural environment. This report synthesises the current state of knowledge on the sources, fate and risks of microplastics pollution. It then focuses on two sources of microplastics pollution, textile products and vehicle tyres, due to their substantial contribution to global microplastics emissions and currently largely absent policy frameworks to mitigate them.