In this issue of Anesthesiology Clinics, guest editors Drs. Ronald G. Pearl and Sean Mackey bring their considerable expertise to the topic of Pain/Palliative Care. Top experts in the field cover key topics such as psychological approaches for migraine management; ketamine in chronic pain management; spinal cord stimulation for treatment of chronic pain: history and transition to novel waveforms; blinded pain cocktails; transitional pain services; and more. - Contains 11 relevant, practice-oriented topics including the emerging field of potential biased opioid agonists; update on treatments for facial pain; disparities in pain medicine; ultrasound-guided procedures in the management of chronic pain; and more. - Provides in-depth clinical reviews on pain and palliative care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Anesthesiology Clinics brings the reader up to date on the most important advances in surgical palliative care for anesthesiology intensivists. Topics covered include recent trends and developments, palliative care of patients on high doses of narcotics, trauma in the surgical ICU, care of family in the surgical ICU, communication skills in palliative surgery, surgical palliative care in Haiti, and much more.

This issue on sex and gender comes at an opportune time, as the DSM-IV is being revised, and in particular sex and gender issues are being reconsidered. This issue focuses on research in the area of gender variant children and transgender adolescents, assessment of several scenarios and clear information on practice parameters. Therapy for gender variant children and transgender adolescents is discussed in detail, as well as parents' perspectives, ethical legal, and non-discrimination issues, and education on these subjects. International standards of care are also discussed.

The volume of elderly patients requiring anesthesia and surgery is growing rapidly. Thirty-five percent of surgeries are performed on patients older than 65 years, and in general, these patients have higher morbidity and mortality rates after anesthesia compared with their younger counterparts. One of the major challenges of treating elderly patients is the heterogeneity of the geriatric population—and the need to individualize care for each patient to provide the best outcome.

Part of the Integrating Palliative Care series, this volume on surgical palliative care guides readers through the core palliative skills and knowledge needed to deliver high value care for patients with life-limiting, critical, and terminal illness under surgical care. Surgical Palliative Care is an ideal resource for surgeons, surgical nurses, intensivists, and other practitioners who wish to learn more about integrating palliative care into the surgical field.

In this issue of Anesthesiology Clinics, guest editors Drs. Athanasios Chalkias, Mary Jarzebowski, and Kathryn Rosenblatt bring their considerable expertise to the topic of Current Topics in Critical Care for the Anesthesiologist. Top experts in the field cover key topics such as perioperative management of the acute stroke patient; traumatic brain injury: intraoperative management and ICU multimodality monitoring; update on mechanical circulatory devices; management of intraoperative cardiac arrest; intraoperative ventilator management of the critically ill patient; and more. - Contains 16 relevant, practice-oriented topics including transfusion thresholds across surgical specialties; delirium prevention and management in frail surgical patients; perioperative fluid management and volume assessment; coagulopathy and emergent reversal of anticoagulation; impact of ICU nutrition on the microbiome and patient outcomes; massive trauma; and more. - Provides in-depth clinical reviews on current topics in critical care for the anesthesiologist, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Anesthesiology Clinics, guest editors Drs. Matthew M. McEvoy and James Abernathy III bring their considerable expertise to the topic of Perioperative Safety Culture. Safety culture is the product of individual and group values, attitudes, perceptions, competencies, and patterns of behavior that determine an organization's health and safety management. In this issue, top experts discuss topics such as patient safety and clinician wellness; handoffs and In-hospital care transitions; team dynamics in the operating room: how is team performance optimized?; anesthesiology operating room medication delivery; OR design: state-of-the-art design concepts to help mitigate errors and improve safety; and more. - Contains 16 practice-oriented topics including perioperative safety culture: principles, practices, and pragmatic approaches; what do we know about the system and what are the best practices to stop errors in healthcare; coaching to improve performance; systems of care delivery and optimization in the preoperative arena, operating room, ICU, and postoperative care wards; and more. - Provides in-depth clinical reviews on perioperative safety culture, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.