Explains how companies must pinpoint business strategies to a few critically important choices, identifying common blunders while outlining simple exercises and questions that can guide day-to-day and long-term decisions.

Cellular Basis of Chemical Messengers in the Digestive System contains the proceedings of an international symposium on the cellular basis of chemical messengers of the digestive system held in Santa Monica, California, on January 16, 17, and 18, 1980. The papers explore the entire spectrum of problems related to the cellular aspects of chemical messengers in the digestive system, with emphasis on which amines and peptides serve these functions and in which neurons and endocrine-paracrine cells each kind of chemical messenger is found. This book is comprised of 28 chapters divided into six sections and begins by considering the nature of gut peptides and their possible functions. The discussion then turns to the diffuse neuroendocrine system and the phylogeny of the gastroenteropancreatic neuroendocrine system. Methods such as immunocytochemistry, electron immunohistochemistry, and electron microscopy autoradiography are then described. The following chapters focus on the function and morphology of endocrine-paracrine cells; immunochemical characterization of peptides in endocrine cells and nerves; Langerhans islets as the neuro-paraneuronal control center of the exocrine pancreas; and regulation of metabolism by gastroenteropancreatic peptides. The final section presents experimental results, including in vitro studies of canine pseudo-islets and of the mechanism of gastrin release. This monograph will be of interest to physiologists and other practitioners in the field of medicine.

An "anatomical" study of building systems integration with guidelines for practical applications Through a systems approach to buildings, Integrated Buildings: The Systems Basis of Architecture details the practice of integration to bridge the gap between the design intentions and technical demands of building projects. Analytic methods are introduced that illustrate the value, benefit, and application of systems integration, as well as guidelines for selecting technical systems in the conceptual, schematic, and design development stages of projects. Landmark structures such as Eero Saarinen's John Deere Headquarters, Renzo Piano's Kansai International Airport, Glenn Murcutt's Magney House, and Richard Rogers's Lloyd's of London headquarters are presented as part of an extensive collection of case studies organized into seven categories: Laboratories Offices Pavilions Green Architecture High Tech Architecture Airport Terminals Residential Architecture Advanced material is provided on methods of integration, including an overview of integration topics, the systems basis of architecture, and the integration potential of various building systems. An expanded case study of Ibsen Nelsen's design for the Pacific Museum of Flight is used to demonstrate case study methods for tracing integration through any work of architecture. Visually enhanced with more than 300 illustrations, diagrams, and photographs, Integrated Buildings: The Systems Basis of Architecture is a valuable reference guide for architecture and civil engineering students, as well as architects, engineers, and other professionals in the construction industry.