OECD Series on Testing and Assessment Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
Title | OECD Series on Testing and Assessment Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 85 |
Release | 2017-04-13 |
Genre | |
ISBN | 9264274790 |
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and ...
OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies
Title | OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 112 |
Release | 2002-12-12 |
Genre | |
ISBN | 9264078495 |
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.
OECD Series on Testing and Assessment Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models
Title | OECD Series on Testing and Assessment Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 154 |
Release | 2014-09-03 |
Genre | |
ISBN | 9264085440 |
This document presents principles and helpful guides for validating (Q)SAR technology for a variety of applications.
OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition
Title | OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 156 |
Release | 2014-09-03 |
Genre | |
ISBN | 9264221476 |
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
OECD Series on Testing and Assessment Guiding Principles and Key Elements for Establishing a Weight of Evidence for Chemical Assessment
Title | OECD Series on Testing and Assessment Guiding Principles and Key Elements for Establishing a Weight of Evidence for Chemical Assessment PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 37 |
Release | 2019-10-22 |
Genre | |
ISBN | 9264696814 |
This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach to WoE. The ultimate goal is to facilitate that regulators follow a consistent, clear and transparent delivery of evidence using the Principles and Elements described in this document. This can be especially helpful for countries with no existing WoE frameworks or those looking to augment their approaches. It also allows for stakeholders to understand a WoE decision-making process, including potential for unreasonable bias. These Guiding Principles and Key Elements can be employed to develop frameworks that range from simple and pragmatic approaches to more elaborate systems, depending on the context.
OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals
Title | OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 118 |
Release | 2014-09-03 |
Genre | |
ISBN | 9264221484 |
This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment
Title | OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 23 |
Release | 2017-04-13 |
Genre | |
ISBN | 9264274820 |
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...