OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies PDF eBook
Author OECD
Publisher OECD Publishing
Pages 15
Release 2018-06-27
Genre
ISBN 9264071180

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies Book in PDF, Epub and Kindle

The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies PDF eBook
Author OECD
Publisher OECD Publishing
Pages 20
Release 2018-06-27
Genre
ISBN 9264071229

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies Book in PDF, Epub and Kindle

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies PDF eBook
Author OECD
Publisher OECD Publishing
Pages 18
Release 2018-06-27
Genre
ISBN 9264071202

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies Book in PDF, Epub and Kindle

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test PDF eBook
Author OECD
Publisher OECD Publishing
Pages 4
Release 1986-10-23
Genre
ISBN 9264071482

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test Book in PDF, Epub and Kindle

The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity PDF eBook
Author OECD
Publisher OECD Publishing
Pages 20
Release 2009-09-08
Genre
ISBN 9264070605

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity Book in PDF, Epub and Kindle

This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study PDF eBook
Author OECD
Publisher OECD Publishing
Pages 14
Release 2018-06-27
Genre
ISBN 9264070826

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study Book in PDF, Epub and Kindle

This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method
Title OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method PDF eBook
Author OECD
Publisher OECD Publishing
Pages 14
Release 2002-02-08
Genre
ISBN 9264071008

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method Book in PDF, Epub and Kindle

This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.