OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 29 |
Release | 2019-06-18 |
Genre | |
ISBN | 9264264612 |
The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight of evidence determination using other existing information.
Test No. 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method
Title | Test No. 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 34 |
Release | 2013-07-26 |
Genre | |
ISBN | 9264203826 |
The present Test Guideline addresses the human health hazard endpoint skin corrosion, following exposure to a test chemical. Skin corrosion is defined as the production of irreversible tissue damage, manifested as visible necrosis of the skin ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 28 |
Release | 2021-06-17 |
Genre | |
ISBN | 9264242848 |
This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2.
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 498: In vitro Phototoxicity - Reconstructed Human Epidermis Phototoxicity test method
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 498: In vitro Phototoxicity - Reconstructed Human Epidermis Phototoxicity test method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 28 |
Release | 2023-07-04 |
Genre | |
ISBN | 9264353089 |
Skin phototoxicity (photoirritation) is defined as an acute toxic response elicited by topically or systemically administered photoreactive chemicals after the exposure of the skin to environmental light. The in vitro reconstructed human epidermis phototoxicity test (RhE PT) is used to identify the phototoxic potential of a test chemical after topical application in reconstructed human epidermis (RhE) tissues in the presence and absence of simulated sunlight.
Test No. 431: In Vitro Skin Corrosion: Human Skin Model Test
Title | Test No. 431: In Vitro Skin Corrosion: Human Skin Model Test PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 8 |
Release | 2004-11-23 |
Genre | |
ISBN | 9264071148 |
The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight of evidence determination using ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER)
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER) PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 15 |
Release | 2015-07-28 |
Genre | |
ISBN | 9264242732 |
This Test Guideline addresses the human health endpoint skin corrosion. It is based on the rat skin transcutaneous electrical resistance (TER) test method, which utilizes skin discs to identify corrosives by their ability to produce a loss of normal stratum corneum integrity and barrier function.
Test No. 439: In Vitro Skin Irritation Reconstructed Human Epidermis Test Method
Title | Test No. 439: In Vitro Skin Irritation Reconstructed Human Epidermis Test Method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 18 |
Release | 2010-07-23 |
Genre | |
ISBN | 9264090959 |
This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2 ...