OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 29 |
Release | 2008-10-16 |
Genre | |
ISBN | 9264071040 |
The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling of chemicals. It is easiest to ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 14 |
Release | 2002-02-08 |
Genre | |
ISBN | 9264071008 |
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 14 |
Release | 2002-02-08 |
Genre | |
ISBN | 926407094X |
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 20 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264284168 |
This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 412: Subacute Inhalation Toxicity: 28-Day Study
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 412: Subacute Inhalation Toxicity: 28-Day Study PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 23 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264070788 |
This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 20 |
Release | 2009-09-08 |
Genre | |
ISBN | 9264070605 |
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 4 |
Release | 1986-10-23 |
Genre | |
ISBN | 9264071482 |
The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...