A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion—with consequential biomedical and public health relevance—of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.

Treatise on Geophysics: Mantle Dynamics, Volume 7 aims to provide both a classical and state-of-the-art introduction to the methods and science of mantle dynamics, as well as survey leading order problems (both solved and unsolved) and current understanding of how the mantle works. It is organized around two themes: (1) how is mantle convection studied; and (2) what do we understand about mantle dynamics to date. The first four chapters are thus concerned with pedagogical reviews of the physics of mantle convection; laboratory studies of the fluid dynamics of convection relevant to the mantle; theoretical analysis of mantle dynamics; and numerical analysis and methods of mantle convection. The subsequent chapters concentrate on leading issues of mantle convection itself, which include the energy budget of the mantle; the upper mantle and lithosphere in and near the spreading center (mid-ocean ridge) environment; the dynamics of subducting slabs; hot spots, melting anomalies, and mantle plumes; and finally, geochemical mantle dynamics and mixing. - Self-contained volume starts with an overview of the subject then explores each topic in detail - Extensive reference lists and cross references with other volumes to facilitate further research - Full-color figures and tables support the text and aid in understanding - Content suited for both the expert and non-expert

A standard text in a variety of courses, the Techniques Manual, as it is commonly called, covers every aspect of modern wildlife management and provides practical information for applying the hundreds of methods described in its pages. To effectively incorporate the explosion of new information in the wildlife profession, this latest edition is logically organized into a two-volume set: Volume 1 is devoted to research techniques and Volume 2 focuses on management methodologies.

Point processes and random measures find wide applicability in telecommunications, earthquakes, image analysis, spatial point patterns, and stereology, to name but a few areas. The authors have made a major reshaping of their work in their first edition of 1988 and now present their Introduction to the Theory of Point Processes in two volumes with sub-titles Elementary Theory and Models and General Theory and Structure. Volume One contains the introductory chapters from the first edition, together with an informal treatment of some of the later material intended to make it more accessible to readers primarily interested in models and applications. The main new material in this volume relates to marked point processes and to processes evolving in time, where the conditional intensity methodology provides a basis for model building, inference, and prediction. There are abundant examples whose purpose is both didactic and to illustrate further applications of the ideas and models that are the main substance of the text.

On antiquities collected by Robert Bruce Foote, 1834-1912 from South India.