This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.

Drs. Huitt and Daley have assembled an expert panel of authors on the topic of Non-Tuberculosis Mycobacteria. Articles in this issue will include discussions in the following areas: The Pathogenesis of NTM, Epidemiology of NTM, Environmental Sources of NTM, Laboratory Diagnosis of NTM, Medications and Monitoring in NTM infections, Treatment of Rapidly Growing NTM, Treatment of Slow Growing NTM, NTM Infections in Immunocompromised Hosts, Extra Pulmonary NTM Infections, NTM Infections in Cystic Fibrosis, and Surgical Approach to NTM Infections.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

In this issue of Clinics in Chest Medicine, guest editors Drs. Shannon Kasperbauer and Rachel Thomson bring their considerable expertise to the topic of Nontuberculous Mycobacterial Pulmonary Disease. Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a challenging infection which is becoming increasingly prevalent, particularly in the elderly, for reasons which are unknown. In this issue, top experts discuss topics such as environmental sources and transmission of nontuberculous mycobacteria; global epidemiology; host susceptibility; investigation and management of bronchiectasis in nontuberculous mycobacterial pulmonary disease; and more. - Contains 15 practice-oriented topics including novel antimicrobial agents in nontuberculous pulmonary disease; host directed therapy in nontuberculous pulmonary disease; cystic fibrosis related nontuberculous mycobacterial pulmonary disease; surgical resection in nontuberculous mycobacterial pulmonary disease; and more. - Provides in-depth clinical reviews on nontuberculous mycobacterial pulmonary disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Dr. Jon Koff has assembled and expert team of authors of the topic of Cystic Fibrosis. Articles include: Epidemiology and Pathobiology, Genetics and genetic medicine in Cystic Fibrosis, Innate and Adaptive Immunity in Cystic Fibrosis, Microbiome in Cystic Fibrosis, Diagnostic Testing in Cystic Fibrosis, Treating Pseudomonas in Cystic Fibrosis, Diagnosis of Adult Patients with Cystic Fibrosis, Transition from Pediatrics to Adult Care, Lung Transplant in Cystic Fibrosis, and more!

The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject. Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed. Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis. Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides. Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.